Adaptation following small bowel resection (SBR) signals enterocyte proliferation and apoptosis. Because p53-induced p21 waf1/cip1 may be important for apoptosis in many cells, we hypothesized that these genes are required for increased enterocyte apoptosis during adaptation. Male C57BL/6 (wild-type) or p53-null mice underwent 50% proximal SBR or sham operation (bowel transection-reanastomosis)...

Abdominal actinomycosis is extremely rare. We report a case of actinomycosis of the small intestine presenting as a perforation and requiring subsequent laparotomy and small bowel resection. Such a description of actinomycosis has not previously been described in the literature.

background: recent researches have led to find strategies to prevent relapse and to improve survival for gastric cancer patients, including preoperative neo-adjuvant approaches. however, the efficacy of some neo-adjuvant regimens including 5-fluorouracil, cisplatin, and docetaxel have been less investigated. the present study evaluated the outcome and mid-term survival of patients with gastric ...

BACKGROUND: The extent of the resection, whether clamped or non-clamping resection is factor that influences operating time and intraoperative bleeding, development modern techniques for vascular control determine lesser blood loss, morbidity, mortality. AIM: aim this study was to experience General Hepatobiliary Surgery Clinic at Aleksandrovska Hospital Sofia, Republic Bulgaria in treatment pa...

Restaging, or second transurethral resection (TUR), is essential to successful management of high-risk, non-muscle-invasive bladder cancer. Here we review the relevant literature documenting the role of restaging TUR. Cohort and randomized studies show that restaging TUR detects more tumors than initial TUR, improves clinical staging, and reduces the frequency of early tumor recurrences. Our co...

OBJECTIVE To examine recurrence and survival rates for patients treated with hepatic resection only, radiofrequency ablation (RFA) plus resection or RFA only for colorectal liver metastases. SUMMARY BACKGROUND DATA Thermal destruction techniques, particularly RFA, have been rapidly accepted into surgical practice in the last 5 years. Long-term survival data following treatment of colorectal l...

BACKGROUND Basal cell carcinoma (BCC) is the most common malignancy with increasing incidence worldwide. The tumor invades surrounding tissues in an irregular pattern via subclinical and microscopic finger-like growths known as subclinical extension. Subclinical extension may be responsible for incomplete resection of the tumor. This study investigates the subclinical extension of BCC. METHOD...

•Necrotizing fasciitis has not previously been reported in association with placement of intraperitoneal port at time of cytoreductive surgery.•Consensus is lacking regarding the placement of intraperitoneal ports at the time of bowel surgery.•Delayed placement of intraperitoneal ports may be considered in patients undergoing bowel resection.