We compared ChromID VRE and Brilliance VRE media for the detection of vancomycin-resistant enterococci (VRE). Using a panel of 28 enterococcal isolates, 10 vanA Enterococcus faecium and three vanA Enterococcus faecalis isolates grew as per manufacturers' instructions whilst growth of two vanC and eight vancomycin-susceptible enterococci was inhibited on both media. Important differences were no...

Objective: Vancomycin resistant enterococci (VRE) are important healthcare associated multidrug resistant organisms because of their easily spread in the hospital environment, difficulty to cure and high mortality rate. The aim of this study was to evaluate in vitro activity of daptomycin and tigecycline against VRE strains isolated from rectal swab samples of hospitalized patients. Methods: Si...

OBJECTIVES Our goal was to compare the activities of lacticin 3147 and nisin, two of the most well characterized lantibiotics, against antibiotic-resistant staphylococci and enterococci. METHODS We determined the MICs of lacticin 3147 and nisin for 20 strains of methicillin-resistant Staphylococcus aureus (MRSA), 20 strains of vancomycin-resistant enterococci (VRE), 6 strains of S. aureus wit...

Vancomycin-resistant enterococci (VRE) are a serious public health threat and leading cause of healthcare-associated infections. Bacterial resistance to antibiotics recommended for the treatment enterococcal infections complicates management these Hence, there is critical need discovery new anti-VRE agents. We previously reported carbonic anhydrase inhibitors (CAIs) as potent VRE inhibitors. In...

This study was conducted to determine the prevalence of vancomycin-resistant enterococci (VRE) in the stools of hospitalized patients with possible antibiotic-associated diarrhoea. From 176 faecal samples collected during 1997 and 1998, 66 strains of enterococci were recovered using vancomycin enrichment techniques. Only six of these displayed reduced susceptibility to vancomycin (MIC 8-12 mg/L...

INTRODUCTION Enterococci are opportunistic pathogens which represent one of the leading agents of nosocomial infections, especially urinary tract infections (UTI) in hospitalized patients. The aim of the present study was to determine the resistance pattern and the type of resistance genes in vancomycin-resistant Enterococcus isolated from an educational hospital in Iran. MATERIALS AND METHOD...

Sir, Linezolid is the first of a new class of antibiotics, the oxazolidinones, recently licensed for clinical use in Portugal (September 2001). This antibiotic has demonstrated good activity against Gram-positive organisms, including strains resistant to multiple antimicrobials, such as vancomycin-resistant enterococci (VRE). However, the emergence of enterococcal isolates resistant to linezoli...

E are intrinsically resistant to many antimicrobial agents and have acquired resistance to commonly used agents, including ampicillin and aminoglycosides. Gylcopeptide antibiotics (including vancomycin) are the main option for treating multi-resistant enterococcus isolates. However, vancomycin-resistant enterococci (VRE) are becoming a major concern in medical practice.1 The VRE fecal colonizat...

The aim of the present study was to evaluate the antagonistic activity of marine Streptomyces sp. VITBRK1 against Methicillin resistance Staphylococcus aures (MRSA) and vancomycin-resistant Enterococci (VRE). Drug resistance by Bacterial pathogens do exhibit significant tolerance to standard antimicrobials during infections and drug resistance currently a growing problem worldwide. A total of 1...

IntroLinezolid, an oxazolidinone antibiotic, was introduced early in 2000 as a new therapeutic option against gram positive cocci including vancomycin resistant enterococci (VRE). People are using linezolid alternative VRE due to which resistance is increasing rapidly leading failure of VRE. So the aims and objectives present study determine prevalence linezolid-resistant (LRVRE) clinical isola...