19 Penicillium spp. are among the major postharvest pathogens of citrus fruit. 20 Induction of natural resistance in fruits constitutes one of the alternatives to 21 chemical fungicides. Here, we investigated the involvement of the 22 phenylpropanoid pathway in the induction of resistance in Navelate oranges by 23 examining changes in the metabolic profile of upon eliciting citrus fruits. By 24...

background: the emergence and spread of chloroquine resistant plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rodent plasmodia . using animal plasmo­dia , particularly primate and rodent plasmodia can be useful model for human plasmodia studies. in this study we have tried to consider and compare the sequence ...

Herein we demonstrated that dinuclear zinc complexes could overcome drug resistance in R-HepG2 drug resistance hepatocellular carcinoma cells through induction of mitochondria-mediated apoptosis or by triggering mitochondria fragmentation, depletion of the membrane potential and intracellular ATP levels.

Background: The development of multidrug resistance (MDR) is a major barrier to achieving effective chemotherapy in cancer. Studies have shown that epithelial ovarian cancer initially responds platinum-based therapy, however, the recurrent type often resistant treatment and associated with high mortality. Fucoxanthin, natural component found marine algae, possesses various pharmacologic propert...

Inducible resistance in plants is a defense strategy for avoiding the negative consequences of herbivory on plant fitness. Since resistance is costly, the induction of resistance may depend on resource availability. Resource-based plant–herbivore hypotheses predict that the cost of producing carbon-based defensive metabolites will be higher when an excess of nutrients is available for growth. W...

activities of thirty bacterial strains obtained from plants rhizosphere in different areas against phytophthora drechsleri were assessed through in vitro and greenhouse experiments. dual culture and extracellular metabolites tests were used in in vitro assays. the bacterial strains inhibited growth of p. drechsleri, the highest inhibition zones was belonged to t17-4 strain with 61.904% in dual ...

conclusions induction of coccoid form of p. aeruginosa may be one of the important reasons for antibiotic treatment failure; therefore, prescribed dose of antibiotics should be carefully managed to prevent increasing antibiotic resistance and coccoid bacteria induction. results all used antibiotics at sub mic concentration had capability to induce coccoid bacteria. the highest rate of induced c...

E2F1 is responsible for the regulation of FOXM1 expression, which plays a key role in epirubicin resistance. Here, we examined the role and regulation of E2F1 in response to epirubicin in cancer cells. We first showed that E2F1 plays a key role in promoting FOXM1 expression, cell survival, and epirubicin resistance as its depletion by siRNA attenuated FOXM1 induction and cell viability in respo...