OBJECTIVES To examine the relation between exposure to acid anhydrides and the risk of developing immediate skin prick test responses to acid anhydride human serum albumin (AA-HSA) conjugates or work related respiratory symptoms; to assess whether these relations are modified by atopy or smoking. METHODS A cohort of 506 workers exposed to phthalic (PA), maleic (MA), and trimellitic anhydride ...

This study was performed to evaluate the prevalence of respiratory symptoms in workers in a petrochemical complex and to elucidate the relationship between the prevalence and work-related factors. A questionnaire was distributed to 5,983 male workers working in a petrochemical complex. As for the respiratory symptoms, cough was present in 2.4%, phlegm in 8.1%, wheezing in 2.8% and shortness of ...

Chemicals are able to cause various forms of allergic disease in susceptible individuals. Among those of greatest importance in the context of occupational disease is chemical respiratory allergy, where allergic sensitization of the respiratory tract is associated with elicitation of rhinitis, asthma and/or other pulmonary symptoms following inhalation exposure to the inducing chemical allergen...

OBJECTIVE To determine the changes in respiratory function within one hour and three hours of exposure to formaldehyde and investigate the relation between exposure to formaldehyde and acute changes in respiratory function. METHOD Respiratory function of 50 non-smoking medical students exposed to formaldehyde in a gross anatomy laboratory were compared with respiratory function of 36 non-expo...

Motor vehicles emit particulate matter < 2.5 microm in diameter (PM(2.5)), and as a result, PM(2.5) concentrations tend to be elevated near busy streets. Studies of the relationship between motor vehicle emissions and respiratory health are generally limited by difficulties in exposure assessment. We developed a refined exposure model and implemented it using a geographic information system to ...

BACKGROUND The prevalence of diagnosed asthma and wheezing in young subjects is increasing; among environmental risk factors, occupational exposure can play a relevant role. STUDY OBJECTIVES The purpose of the study was to evaluate the effects of occupational exposure to a large variety of irritants and/or sensitizers on the incidence of respiratory symptoms and pulmonary function impairment ...

SCHAEFER, KARL E., NANCY MCCABE, AND JUDITH WITHERS. Stress response in chronic hypercajmia. Am. J. Physiol. 214(3) : 543-548. 1968.-Respiratory acidosis induced by prolonged exposure of guinea pigs to 15% COz in 21y0 O2 was compensated after 3 days of exposure. Adrenal cortical response as measured by a rise of blood corticosteroids, adrenal cholesterol depletion, and lymphopenia was limited t...

OBJECTIVE To investigate the occurrence of chronic respiratory effects of exposure to organic dust in the potato processing industry. METHODS Self reported chronic respiratory symptoms and spirometric lung function were assessed in a cross sectional study among 135 potato processing workers. A comprehensive study of current exposure to dust, endotoxin, and potato antigens had been performed p...