G ood news: A long-awaited model for uterine fibroid tumor research is upon us (1). Historically, there has been a paucity of in vivo models for the study of fibroid tumors (i.e., leiomyomas), benign female pelvic organ tumors characterized by clonal proliferation of smooth muscle cells and expression of genes involved in fibrosis and extracellular matrix (ECM) production. This is staggering, c...

A the microscope came into vogue, the surgeons enjoyed a huge optical advantage, but at the price of increasing the working distance. This often resulted in early fatigue of the shoulder, arm and hand muscles and also predisposed to tremors very soon. The stability of the surgeon’s hand and the surgeon’s fatigue cannot be measured, and the impressions of the surgeons using the system are theref...

T he article by Haben 1 in this issue of Medical Problems of Performing Artists describes one expert clinician's approach to the use of rest in treating voice problems in singers. In the absence of well-designed randomized controlled trials of voice rest for various vocal problems (and little in the way of other research on the topic), expert opinion is the best guidance available. Performing a...

The Representational State Transfer (REST) architectural style has seen substantial growth and adoption for the design of modern Resource-Oriented Architectures. However, the impact of fundamental constraints such as stateful resources, stateless interactions, and the uniform interface have had only limited uptake and impact in the Business Process Modeling (BPM) community in general, and in th...

Today’s applications are developed in a world where the execution context changes continuously. They have to adapt to these changes at run-time if they want to offer their services without interruption. This is particularly critical for distributed Web applications, whose components run on different machines, often managed by different organizations. Designing these programs in an easy and effe...