Keratoconus associated with myelinated retinal nerve fibers is not frequent and the relationship between the two pathologies is difficult to explain, therefore studies and further investigation are required. The etiology of each condition may suggest the role of genetic factors. Follow-up is important to evaluate the progression of keratoconus and myelination. Here we describe the unusual coexi...

A low-resolution path-length-multiplexed scattering angle diverse optical coherence tomography (PM-SAD-OCT) is constructed to investigate the scattering properties of the retinal nerve fiber layer (RNFL). Low-resolution PM-SAD-OCT retinal images acquired from a healthy human subject show the variation of RNFL scattering properties at retinal locations around the optic nerve head. The results ar...

PURPOSE To present a new retinal layer segmentation technique for evaluation of nerve fiber hyperplasia in patients with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). METHODS Five patients with a molecular diagnosis of ARSACS and five age- and sex-matched healthy controls underwent a full ophthalmologic examination, which included a new technique to segment the retinal l...

OBJECTIVES To longitudinally evaluate optical coherence tomography (OCT) peripapillary retinal nerve fiber layer thickness measurements and to compare these measurements across time with clinical status and automated perimetry. METHODS Retrospective evaluation of 64 eyes (37 patients) of glaucoma suspects or patients with glaucoma participating in a prospective longitudinal study. All partici...

background: optical coherence tomography (oct) is a simple, high-resolution technique to quantify the thickness of retinal nerve fiber layer (rnfl) and macula volume, which provide an indirect measurement of axonal damage in multiple sclerosis (ms). this study aimed to evaluate oct finding in relapsing-remitting ms patients of the northwest of iran and compare them with a normal control group. ...

PURPOSE To investigate the influence of intersubject variation in ocular parameters on the mapping of retinal locations to the retinal nerve fiber layer and optic nerve head. METHODS One hundred retinal nerve fiber layer (RNFL) bundle photographs from 100 subjects were optimized digitally and single RNFL bundles manually traced back to the ONH where their entry point was noted. A 24-2 visual ...

PURPOSE The retinal nerve fiber layer (RNFL) exhibits birefringence that is due to the oriented cylindrical structure of the ganglion cell axons. Possible birefringent structures include axonal membranes, microtubules (MTs), and neurofilaments. MTs are generally assumed to be a major contributor, but this has not been demonstrated. In this study, the MT depolymerizing agent colchicine was used ...

1) Evaluation of the Optic Nerve requires descriptive quantitative and qualitative intrapapillary and parapapillary regions of the optic nerve head and the retinal nerve fiber layer (RNFL)variables including: a. Size and shape of the optic disc b. Size, shape and pallor of the neuroretinal rim c. Configuration and depth of the optic cup d. Cup-disc diameter ratio and cup-disc area ratio e. Posi...

This report is of a patient with ischemic central retinal vein occlusion who underwent panretinal photocoagulation. Serial measurements of the retinal nerve fiber layer were performed using scanning laser polarimetry, which showed increased thickness of the peripapillary region as early as 2 weeks after the panretinal photocoagulation.

Glaucoma is a progressive optic neuropathy, characterized by loss of retinal ganglion cells and retinal nerve fiber layer as well as visual field loss. Therefore, in glaucoma, the correlation between structure and function is important, since it can be useful for tracking glaucomatous changes and for following the progression of the disease.