Abstract A hybrid of montmorillonite (Mnt) and rifampicin (RIF) was synthesized the structure stability drug carrier system clarified. Density functional theory calculations involving dispersion corrections (DFT-D3) were performed to characterize interactions acting in interlayer space intercalated with rifampicin. The RIF-Mnt complex determined. Calculations revealed deformation molecular afte...

BACKGROUND In patients with intrathoracic lymphadenopathy, differentiating tuberculosis from sarcoidosis is often difficult. We hypothesized that Xpert MTB/RIF assay, a semi-automated hemi-nested PCR would help in this regard. OBJECTIVE To evaluate the performance of Xpert MTB/RIF in the differential diagnosis of tuberculosis and sarcoidosis. METHODS This was a retrospective analysis of pat...

Selective retrieval practice of category exemplars often impairs the recall of related items, a phenomenon known as retrieval-induced forgetting (RIF). In Experiment 1 the role of item typicality (high, low) and presentation format of category exemplars (random, grouped) were analysed, while in Experiment 2 two encoding strategies (inter and intracategory) to modulate RIF were tested. Exemplar ...

Results: Approximately 11.6% of the strains were resistant against at least one major drug, and 8.3% were resistant against more than one drug. Single-drug resistance for INH, ETB, SM, and RIF was found as 5.8%, 2.1%, 3.7%, and 0.0%, respectively. Two or more drug resistance rates for SM + ETB, SM + INH, INH + RIF, RIF + ETB, INH + ETB + RIF, SM + ETB + INH and INH + ETB + RIF + SM were determi...

We read with interest through the remarks made by Dr. Alland and colleagues (1), in response to our recent observations published in the Journal of Clinical Microbiology (2). We would like to offer responses to their comments below. Dr. Alland and colleagues consider that our findings favored the line probe assay (LPA) over the Xpert MTB/RIF assay because according to them (i) our findings are ...

Here we demonstrated that SKI2162, a small-molecule inhibitor of the TGF-β type I receptor (ALK5), prevented radiation-induced fibrosis (RIF) in mice. SKI2162 inhibited phosphorylation of Smad and induction of RIF-related genes in vitro. In RIF a mouse model, SKI2162 reduced late skin reactions and leg-contracture without jeopardizing the acute skin reaction. Irradiation of mouse tissue increas...

Selectively retrieving a subset of previously studied information can cause forgetting of related, nonretrieved information. Such retrieval-induced forgetting (RIF) has typically been attributed to inhibitory control processes. Examining participants with a mean age of about 70 years, previous work reported intact RIF in older adults, suggesting efficient inhibition in older adults' episodic me...

Selectively retrieving a subset of previously studied information can cause forgetting of related, nonretrieved information. Such retrieval-induced forgetting (RIF) has typically been attributed to inhibitory control processes. Examining participants with a mean age of about 70 years, previous work reported intact RIF in older adults, suggesting efficient inhibition in older adults’ episodic me...

A rifampin-susceptible strain (VSV Rif+) was selected from the wild vesicular stomatitis virus (VSV) population unsusceptible to rifampin. The VSV Rif+ was blocked in its intracellular replication in the presence of rifampin. In cells, rifampin affected primarily VSV Rif+ transcription, but to a different extent than in a cell-free system. In addition, a decrease in the amount of VSV Rif+ prote...

BACKGROUND Xpert MTB/RIF assay is a highly sensitive test for TB diagnosis, but still costly to most low-income countries. Several implementation strategies instead of frontline have been suggested; however with scarce data. We assessed accuracy of different Xpert MTB/RIF implementation strategies to inform national roll-out. METHODS This was a cross-sectional study of 1,924 adult presumptive...