To ensure that clinical research arrives at the "right" answers to the right questions for patients, studies should be designed to more closely approximate real-world use of therapeutics and devices.

This paper introduces the DSLGen (Domain Specific Language Generator), an execution platform independent program generation system that produces optimized code (without reprogramming) for multiple execution platform architectures. The target computation is specified in a programming language independent, Implementation Neutral Specification (INS) form and need not ever be changed unless the tar...

The neats: proponents of formal-based, knowledge-intensive smart systems to revolutionize the requirements process. The eventual success of the neat approach is less certain. There are several opinions of the answer to: ‘Can the neats ever playa significant role in requirements engineering?’: a. Never – the extra effort of doing things the neat way will always exceed the payoff. b. Hardly ever ...

efforts to achieve effective and meaningful patient and public involvement (ppi) in healthcare have existed for nearly a century, albeit with limited success. this brief commentary discusses a recent paper by carter and martin exploring the “challenges facing healthwatch, a new consumer champion in england,” and places these challenges in the context of the broader struggle to give a voice to h...