OBJECTIVES To study the effect of mitral valve repair with or without concomitant tricuspid valve repair on functional tricuspid regurgitation and right ventricular function. METHODS From 2001 to 2007, 1833 patients with degenerative mitral valve disease, a structurally normal tricuspid valve, and no coronary artery disease underwent mitral valve repair, and 67 underwent concomitant tricuspid...

Background Surgical ventricular restoration (SVR) after anterior myocardial infarction with post infarction aneurysm, significantly improves left ventricular (LV) performance. To describe mid-term postoperative changes of shape and performance of the newly created LV and mitral valve function through the classical (SI) and apical (ASI) left ventricular sphericity index, and determinants of mitr...

OBJECTIVE Right ventricular dysfunction is a poorly understood but persistent clinical problem. This study was undertaken to evaluate ventricular performance and beta-adrenergic receptor signaling in a tricuspid regurgitation model of right ventricular overload. METHODS Seventeen dogs were chronically instrumented with epicardial dimension transducers. By means of the shell-subtraction model,...

The effect of reducing systemic arterial pressure with an arteriovenous fistula on left and right ventricular myocardial blood flow was studied in 17 anaesthetised, open chest, autonomically blocked dogs. Global and regional myocardial blood flows were measured with radioactive microspheres. As mean arterial pressure was reduced from 133 mmHg to 78 mmHg left ventricular myocardial blood flow an...

conclusions our results demonstrated the ability of pw-tdi and s/sr modalities in detection of the early subclinical abnormalities in asymptomatic patients with significant chronic ar. results ar group had significantly increased lv end systolic and end diastolic volumes, interventricular septum and posterior wall thickness compared to controls. in ar, sm and em of septal wall, sm of lateral wa...

Background The presence of myocardial late gadolinium enhancement (LGE) in patients with sarcoidosis is a powerful predictor of major adverse events (MAE: death, ventricular tachycardia, or appropriate ICD therapy). In this study, we aim to determine if the burden of LGE, left ventricular (LV) and right ventricular (RV) end-diastolic and end-systolic volume index (EDVi & ESVi) and ejection frac...

background: more diagnostic techniques require a better understanding of the forces and stresses developed in the wall of the left ventricle. the aim of this study was to differentiate significant coronary artery disease (cad) patients using a non-invasive quantification of myocardial wall stress in the diastole phase. methods: sixty male subjects with sinus rhythm (30 patients with significant...

The ability to quantitate the amount of permanent left ventricular dysfunction in patients with unstable ischemic heart disease would have important clinical value. Left ventricular function curves were constructed in sixteen patients with acute myocardial infarctions and five patients with unstable angina pectoris syndrome at an average of 56 hours (+/- 8) after the onset of symptoms. Fifty ml...