Permeability at high temperature is a very important parameter to be considered for designing underground high level nuclear waste repository (HLW) in rock mass. The surrounding rock mass is exposed to heat radiated by HLW when it is buried underground and development or extension of micro-cracks takes place in the host rock due to rise in temperature. Keeping this in view, the permeability stu...

The Rho/ROCK pathway plays important roles in the modulation of the cytoskeletal integrity of cells, the synthesis of extracellular matrix components in the aqueous humor outflow tissue and the permeability of Schlemm's canal endothelial cells. The activation of the Rho/ROCK pathway results in trabecular meshwork (TM) contraction, and the inhibition of this pathway would provoke relaxation of T...

SINCE MYOCARDIAL INFARCT SIZE is the major contributor to the development of heart failure, interventions aiming to limit irreversible damage of ischemic myocardium are essential. In the clinical setting, reduction of myocardial oxygen demand and restoration of blood flow to the ischemic myocardium remain the primary targets to accomplish this goal, despite experimental evidence that reperfusio...

background and objectives: in the last few decades, losses of our cultural heritage due to biodeteriorationare beinghighly recognized. from museum objects to rock monuments, the microbial biodeterioration agents are found to be the most destructive. possibilities for proper preservative measure(s) are always more when it is only a monument, statue, museum article, or pre-historic art in any sma...

Laboratory tests were performed on 54 large size specimens of jointed rock mass under uniaxial loading conditions. Based on this experimental study, a methodology has been suggested to estimate strength and tangent modulus of rock masses through a weakness coefficient. The methodology involves mapping of joints in the field and laboratory testing of intact rock specimens to arrive at rock mass ...

Point load testing is used to determine rock strength indexes in geotechnical practice. The point load test apparatus and procedure enables economical testing of core or lump rock samples in either a field or laboratory setting. In order to estimate uniaxial compressive strength, index-to-strength conversion factors are used. These factors have been proposed by various researchers and are depen...