Autism is characterized by inappropriate social interactions, deficits in verbal communication and facial expressions, and ritualistic and repetitive behaviors. Recent evidence suggests the gaseous neurotransmitter nitric oxide (NO) may regulate certain behaviors characterized by autism-like symptoms. Inhibition of NO leads to hyperaggression and excessive mounting which may represent inappropr...

In addition to the classical nuclear receptor pathway, there is a non-genomic pathway in the cell membrane that regulates gene expression in animal steroid hormone signaling; however, this mechanism is unclear. Here, we report that the insect steroid hormone 20-hydroxyecdysone (20E) regulates calcium influx via phospholipase C gamma 1 (PLCG1) to modulate the protein kinase C (PKC) phosphorylati...

W e define t h e no t i on of an inductively defined type in t h e Calculus of C o n s t r u c t i o n s a n d show how induc t ive ly defined types can be represen ted by closed t y p e s . W e show t h a t all p r imi t ive recursive funct ionals over these induct ive ly defined types a r e also r ep resen tab le . Th i s general izes work by B o h m & Be ra rducc i on synthes is of funct ion...