Honeybees produce honey, royal jelly, propolis, bee venom, bee pollen, and beeswax, which potentially benefit to humans due to the bioactives in them. Clinical standardization of these products is hindered by chemical variability depending on honeybee and botanical sources, but different molecules have been isolated and pharmacologically characterized. Major honey bioactives include phenolics, ...

objective: this study aimed to evaluate the effects of royal jelly (rj) on serum biochemical alterations and oxidative stress status in liver and pancreas of streptozotocin (stz)- induced diabetic rats. materials and methods: in this experimental study, thirty two male wistar rats were divided into the following four groups (n=8/group): i. control (c), ii. diabetic (d), iii. royal jelly (r), an...

BACKGROUND Traditional medicines and health supplements have historically been used to treat many illnesses but most of them have not been evaluated objectively to prove their efficacy. We have been investigating the effects of royal jelly (RJ) supplements on acetic acid-induced colitis on the distribution of CD3(+), CD5(+), CD45(+) T-cell and CD68(+) cells in rats. METHODS The rats were divi...

BACKGROUND/AIM Our objective was to identify the antioxidant properties of honeybee products from Turkey, chestnut honey, pollen, propolis, and royal jelly, and their hepatoprotective activity against CCl4-induced hepatic damage in rats. MATERIALS AND METHODS Animals were fed with honeybee products for 7 days following CCl4 injection. Development of liver damage and oxidative stress were moni...

Until now, the properties of honey have been defined based exclusively on the content of plant components in the nectar of given plant. We showed that apalbumin1, the major royal jelly (RJ) protein, is an authentic and regular component of honey. Apalbumin1 and other RJ proteins and peptides are responsible for the immunostimulatory properties and antibiotic activity of honey. For the quantific...

The 2011 highly publicised Nature paper by Kamakura on honeybee phenotypic dimorphism, (also using Drosophila as an experimental surrogate), claims that a single protein in royal jelly, Royalactin, essentially acts as a master "on-off" switch in development via the epidermal growth factor receptor (AmEGFR), to seal the fate of queen or worker. One mechanism proposed in that study as important f...

Transcriptome sequencing has become the main methodology for analyzing the relationship between genes and characteristics of interests, particularly those associated with diseases and economic traits. Because of its role of functional food for humans, commercial royal jelly (RJ) and its production are major research focuses in the field of apiculture. Multiple lines of evidence have demonstrate...

In colony collapse disorder (CCD), honey bee colonies inexplicably lose their workers. CCD has resulted in a loss of 50 to 90% of colonies in beekeeping operations across the United States. The observation that irradiated combs from affected colonies can be repopulated with naive bees suggests that infection may contribute to CCD. We used an unbiased metagenomic approach to survey microflora in...

The western honeybee, Apis mellifera is a prominent model organism in the field of sociogenomics and a recent upgrade substantially improved annotations of the reference genome. Nevertheless, genome assemblies based on short-sequencing reads suffer from problems in regions comprising e.g. multi-copy genes. We used single-molecule nanopore-based sequencing with extensive read-lengths to reconstr...

Absorption of Radioactive Phosphorus by Mycorrhizal Roots of Pine: Paul J. Kramer and Karl M. WiWbur ............. A Qualitative Analysis of the Amino Acids in Royal Jelly: John J. Pratt, Jr. and Howard L. House ... The Effect of 7-Ketocholesterol on the Rabbit: R.H.Cox andE. Y. Spencer .......................... Survey of Chinese Drugs for Presence of Antibacterial Substances: H. Zanyin Gaw an...