Ursolic acid (1) and a new flavanone, 5-O-(6-rhamnosylglucoside)-7-hydroxy-4'-methoxyflavanone (2), were isolated from the leaves of Salvia elegans Vahl. These natural products displayed antidepressant activity in mice as determined by means of a forced swimming test (FST) evaluation. Structural elucidation was carried out by chemical derivatization (acetylation) and spectroscopic analyses, suc...

Radiation-induced oxidative stress and haematopoietic genomic instability is the major concern during planned or unplanned exposure. Use of natural phytochemicals an emerging strategy to prevent from harmful effects radiation. In current investigation, Quercetin 3-Rutinoside (Q-3-R), a polyphenolic bioflavonoid, has been evaluated against gamma radiation (2Gy) induced genotoxic damage imbalance...

The current status of research on polyphenolic compounds in the berries of edible honeysuckle and their biological effects, including recommended utilization, are reviewed. The major classes of phenolic compounds in the blue berried honeysuckle are flavonols (quercetin, rutin, quercitrin) and flavanes (proanthocyanidins, catechins) and anthocyanins. Cyanidin-3-glucoside and cyanidin-3-rutinosid...

Bioactive polyphenolics are ubiquitously present in plants and may play an important role in the prevention and management of certain human diseases. Three known flavonoids viz Kaemperol-3-O-rutinoside (1), quercetin-3-O-glucoside (2) and kaemperol-3-O-glucoside (3) and inseparable mixture (1:1) of quercetin-3-O-glucose/galactose (4) were isolated, and identified for the first time from Holarrh...

the anthocyanins of the fruit skin of iranian forest pear (sange khouj) were separated, identified and quantified using high-performance liquid chromatography/diode array detection (hplc/dad) and hplc/electrospray ionization /mass spectrometry (hplc/esi /ms). the individual anthocyanins were identified by comparing their mass spectral data and retention times with those of standards and publish...

This study examined the effects of freezing, storage, and cabinet drying on the anthocyanin content and antioxidant activity of blueberries (Vaccinium corymbosum L). Fresh samples were stored for two weeks at $\5^\circ$ C while frozen samples were kept for up to three months at $-20^\circ$ C. There were two drying treatments, one including osmotic pretreatment followed by cabinet drying and the...

Four neolignans, (7S,8S)-dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucopyranoside (1), 9′-O-β-D-glucopyranoside (2), (7S,8R)-5-methoxydihydrodehydrodiconiferyl 4-O-β-D-glucopyranoside (3), and (4) five flavonol glycosides, kaempferol-3-O-β-D-glucopyranoside (5), kaempferol 3-O-rutinoside (6), 3-O-α-L-rhamnopyranosyl (1→6)-β-D-galactopyranoside (7), 3-O-β-D-galactopyranoside (8), quercetin 3-O-...

Introduction Reactive oxygen species (ROS) have been shown to play a critical role in many diseases such as diabetes mellitus, cancer, Alzheimer, arteriosclerosis and other conditions. Chronic glucose levels in blood or cells of diabetic patients are known to cause oxidative damages, followed by an increasing in ROS production and/or dysfunction of antioxidant defense system (enzyme or non-enzy...