The aim of this work is to determine an effective yield criteria for porous pressure sensitive solids by employing a virtual testing strategy. focus on the sensitivity typically displayed geomaterials, such as sandstone. Virtual strategy based computational homogenisation approach following unified variational formulation, which provides bounds material properties given choice Representative Vo...

Carbon/Carbon composites finds its applications in several high temperature the field of Space, Aviation etc. Designing components or sub systems with carbon/carbon is a challenging task. It requires prediction elastic properties very accuracy. The can be normally done by analytical, numerical experimental methods. At design stage designers resort to predictions as methods are not feasible duri...

Abstract Material modeling using modern numerical methods accelerates the design process and reduces costs of developing new products. However, for multiscale heterogeneous materials, well-established homogenization techniques remain computationally expensive high accuracy levels. In this contribution, a machine learning approach, convolutional neural networks (CNNs), is proposed as efficient s...

Scale separation is often assumed in most homogenization-based topology optimization (TO) frameworks for design of material microstructures. This work goes beyond the mainstream TO contributions by abandoning scale hypothesis. First, it puts to evidence limits approach when size Representative Volume Element (RVE) not negligible with respect structure. Then, a re-localized scheme bridging RVE a...

The Representative Volume Element (RVE) plays a central role in the homogenization of random heterogeneous microstructures, especially for composite and porous materials, with view to predicting their effective properties. A quantitative evaluation its size is proposed this work linear elasticity thermal conductivity materials. RVE can be associated different physical statistical properties mic...

The RTM (Resin Transfer Molding) manufacturing process is largely used for the fabrication of textile composites. During forming phase, deformations composite reinforcements at mesoscopic scale, such as positions, orientations, and changes in sections deformed yarns, are essential to calculate permeability reinforcement injection phase evaluate mechanical behaviors final products. However, mode...

Knowledge about biological factors involved in exercise-induced angiogenesis is to date still scanty. The present study aimed to investigate the angiogenic stimulus of resistance exercise with and without superimposed whole-body vibrations. Responses to the exercise regimen before and after a 6-week training intervention were investigated in twenty-six healthy male subjects. Serum was collected...

In the breast of adult women, glandular and fat tissues are intermingled and cannot be clearly distinguished. This work studies if this mixture can be treated as a homogenized tissue. A mechanical model is proposed for the mixture of tissues as a function of the fat content. Different distributions of individual tissues and geometries have been tried to verify the validity of the mixture model....

A model to predict the effective stiffness of woven fabric composite materials is presented. Taking advantage of the inherent periodicity of woven fabric architecture, periodic microstructure theory is used at the mesoscale for the case of a two-phase heterogeneous material with multiple periodic inclusions. For plain weave fabrics, the representative volume element (RVE) is discretized into fi...

BACKGROUND Although rotavirus vaccines have been licensed in Spain for over 8 years, they are not funded by its public health systems. The analysis of their effectiveness in the Valencia Region could better inform decisions about potential inclusion in the official immunization schedule. Our aim was to assess the effectiveness of Rotarix® (RV1) and RotaTeq® (RV5) against rotavirus hospitalizati...