BACKGROUND Several studies have supported the antidepressant effects of curcumin (from the spice turmeric) and saffron for people with major depressive disorder. However, these studies have been hampered by poor designs, small sample sizes, short treatment duration, and similar intervention dosages. Furthermore, the antidepressant effects of combined curcumin and saffron administration are unkn...

sepals and petals are byproducts from saffron production process that waste without any use in iran. these byproducts containing a lot of anthocyanin and natural antioxidants.the aim of this study is determine efficiency of extraction and measurement of antioxidant activity and anthocyanin pigments of pollen and anther of saffron flower ,using mixed solvent of ethanol and hydrochloridic acid 1....

OBJECTIVES We have investigated the effect of a saffron supplement, given at a dose of 100 mg/kg, on prooxidant-antioxidant balance (PAB) in individuals with metabolic syndrome. MATERIALS AND METHODS A randomized, placebo-controlled trial design was used in 75 subjects with metabolic syndrome who were randomly allocated to one of two study groups: (1) the case group received 100mg/kg saffron ...

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BACKGROUND Saffron extract, a natural product, has been shown to induce apoptosis in several tumor cell lines. Nevertheless, the p53-dependency of saffron's mechanism of action in colon cancer remains unexplored. MATERIAL AND METHODS In order to examine saffron's anti-proliferative and pro-apoptotic effects in colorectal cancer cells, we treated two p53 isogenic HCT116 cell lines (HCT wildtyp...

An NMR analytical protocol is proposed to characterize saffron samples of different geographical origin (Greece, Spain, Hungary, Turkey and Italy). A microwave-assisted extraction procedure was developed to obtain a comparable recovery of metabolites with respect to the ISO specifications, reducing the solvent volume and the extraction time needed. Metabolite profiles of geographically differen...

Tissue culture is useful method for large scale production of healthy corms and also avenues for creating variability through in vitro use of mutagens and polyploidizing agents. Induction of callus and subsequent regeneration of plants is suggested as possible means of introducing new variation. In vitro micropopagation for product formation its utility is increasing the amount of crocin, picro...

Crocins, the glucosides of crocetin, are present at high concentrations in saffron stigmas and accumulate in the vacuole. However, the biogenesis of the saffron chromoplast, the changes during the development of the stigma and the transport of crocins to the vacuole, are processes that remain poorly understood. We studied the process of chromoplast differentiation in saffron throughout stigma d...

Abstract Saffron ( Crocus sativus L., Iridaceae) is a highly valued species in the food, medicinal, and nutraceutical industries as coloring, flavoring, therapeutic agent. Its productivity flower production vary depending on different factors, including fertilizer treatment. This study was conducted to evaluate effects of inorganic (NK) combined with organic matter plant densities well influenc...

Predatory phytoseiid mites as biocontrol agents are increasingly used in pest control programs across the globe, and Neoseiulus cucumeris (Oudemans) is one of them, which a commercially available agent against various pests greenhouse crops. This generalist predatory mite can feed on different foods diets, including small arthropods pollen. Feeding reproducing pollen diet considerable character...