introduction:  the use of radioactive iodine (131i) has become an important adjunct to the treatment of thyroid cancer and hyperthyroidism. salivary gland has the ability to concentrate radioactive iodine under normal circumstances. salivary gland dysfunction and dry mouth are the common side effectsof high-dose radioiodine therapy. the purposeof this study was to determine the absorbed dose of...

introduction: malignant salivary gland tumors are rare entities. despite advances in surgery, radiation therapy and chemotherapy, the rate of the mortality and five-year survival has not been improved markedly over the last few decades. the activation of egfr- ras-raf signaling pathway contributes to the initiation and progression of many human cancers, promising a key pathway for therapeutic m...

a case of pleomorphic adenoma in sweat gland is reported here. the histopathologic report confirmed the diagnosis. pleomorphic adenoma is most common in salivary glands but very rare in sweat glands. pleomorphic adenoma in sweat gland and the similar tumors of eccring sweat gland are described that bear a striking resemblance to pleomorphic adenomas of salivary gland. upon closer examination, t...

neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes. approximately 70% of the salivary gland tumors affect parotid gland with the submandibular gland being affected in 5-10% of the cases, sublingual gland in 1% and minor glands in 5-15% of the cases. submandibular gland tumors are relatively rare and...

introduction: high-dose radioactive iodine therapy in differentiated thyroid cancer (dtc) may adversely affect the salivary gland function. this study is aimed to evaluate the effect of radioactive iodine (rai) with dose of 100 mci in dtc patients compared to lower doses of less than 30 mci in hyperthyroid cases. methods: fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...

A solitary fibrous tumour is an unknown neoplasm that fibroblastic in nature. It causes diagnostic difficulty due to its unexpected Immunophenotypic appearance as well wide histologic appearance, but most of the time it accurately diagnosed histological characteristics and strong positivity CD34 expression.SFT known occur almost all parts body including meninges skin. This a slow-growing can be...

BACKGROUND Adenoid cystic carcinoma is a locally aggressive salivary gland neoplasm, which has a poor long-term prognosis. A chromosomal translocation involving the genes encoding the transcription factors, MYB and NFIB, has been recently discovered in these tumors. METHODS MYB translocation and protein expression were studied in 37 adenoid cystic carcinomas, 112 other salivary gland neoplasm...

Sebaceous adenomas of the major salivary glands are uncommon tumors. Although sebaceous differentiation within the major salivary glands is a frequent histopathologic finding (approximately 20% to 42% of parotid glands), sebaceous neoplasms of salivary gland origin are not. A number of publications review the clinical and histologic features of sebaceous neoplasms, however, these reports focus ...