Severe iodine deficiency results in impaired thyroid hormone synthesis and thyroid enlargement. In the United States, adequate iodine intake is a concern for women of childbearing age and pregnant women. Beyond this high risk group iodine deficiency is not considered to be a significant problem. This case report describes a 12-year-old male with severe iodine deficiency disorder (IDD) resulting...

Crystals of a 26-nucleotide pseudoknot RNA, PK26, have been grown. The RNA was produced using phosphoramidite chemistry and was purified by denaturing polyacrylamide electrophoresis. The crystallization was robust with respect to changes in the number of nucleotides and to the salt used as precipitant. The crystals belong to space group P4(1)22 or P4(3)22 with unit-cell dimensions a = b = 61.6,...

HEAT AND HYDRATION MAY NOT BE THE FIRST CONSIDERATIONS OF TOURNAMENT DIRECTORS, COACHES, AND ATHLETES, WHEN PREPARING FOR TENNIS. HOWEVER, HEALTH RISKS AND PERFORMANCE DECREMENTS ARE ASSOCIATED WITH BOTH. THE DEMANDS OF TENNIS, PARTICULARLY DURING MULTIDAY TOURNAMENTS, PREDISPOSE PLAYERS TO INCREASED CORE BODY TEMPERATURE AND LARGE FLUID LOSSES. THIS COMBINATION OF FACTORS CAN LEAD TO DECREASED...

Congenital adrenal hyperplasia (CAH) is a rare congenital disorder, which in cases of female genotype may result in virilization. Specific enzyme deficiencies in adrenocorticoid hormones biosynthetic pathway lead to excess androgen production causing virilization. Classic type presents early in infant life as salt losing or simple virilizing type, whereas non classic form presents late at puber...

Salvarsan, the trade name for the hydrochloride of arseno-amino phenol, is suitable, readily oxidising in the presence of air, forming highly toxic compounds of a grey or brownish colour, and slowly soluble in both water and saline. By replacement of a hydrogen group in the phenol radicles by sodium, a salt is formed which is less toxic and rather more soluble in water, but the destruction of t...

The increased unidirectional sodium influx found when human erythrocytes are suspended in isotonic salt solutions containing bicarbonate ions as a replacement for chloride ions was examined. The increased sodium movement appears to have the transport characteristics of anion movement. Inhibitors of anion transport such as furosemide, fluorodinitrobenzene (FDNB), and 4-acetamido-4'-isothiocyano-...

Severe iodine deficiency results in impaired thyroid hormone synthesis and thyroid enlargement. In the United States, adequate iodine intake is a concern for women of childbearing age and pregnant women. Beyond this high risk group iodine deficiency is not considered to be a significant problem. This case report describes a 12-year-old male with severe iodine deficiency disorder (IDD) resulting...

A novel Brönsted-Lewis acidic heteropoly organic-inorganic salt has been prepared via the replacement of protons in neat phosphotungstic acid with both organic and metal cations. This hybrid catalyst, Sm0.33[TEAPS]2PW12O40, exhibited satisfactory performance in the dimerization of rosin to prepare polymerized rosin Under optimum conditions (15.0 g rosin and 5.0 g Sm0.33[TEAPS]2PW12O40 catalyst ...

Mercury substitution is a big issue in electroanalysis, and the search for a suitable, and less toxic, replacement is still under development. Of all the proposed alternatives, bismuth films appear to be the most viable solution, although they are still suffering some drawbacks, particularly the influence of deposition conditions and linearity at low concentrations. In this paper, the most prom...

We previously demonstrated a differential activation of the endothelin-1 (ET-1) pathway in male and female deoxycorticosterone (DOCA)-salt hypertensive rats, with the male rats exhibiting marked alterations in vascular and pressor responses to ET-1 and Suc-[Glu,(9)Ala(11,15)]-ET-1(8-21) (IRL-1620), an ET(B) agonist. Mechanisms underlying these gender differences are unclear, and we hypothesized...