نتایج جستجو برای: sca
تعداد نتایج: 4214 فیلتر نتایج به سال:
BACKGROUND The World Health Organization has declared Sickle Cell Anemia (SCA) a public health priority. There are 300,000 births/year, over 75% in Africa, with estimates suggesting that 6 million Africans will be living with SCA if average survival reaches half the African norm. Countries such as United States of America and United Kingdom have reduced SCA mortality from 3 to 0.13 per 100 pers...
SCA (Service Component Architecture) is a collaborative effort by the leading vendors in the enterprise software space to define an architecture for building applications and systems using a ServiceOriented Architecture. SCA allows developers to define components that implement business logic, which offer their capabilities through services and consume functions offered by other components thro...
OBJECTIVES The radiographic changes of mandibular bone texture was evaluated in patients with sickle cell anemia (SCA) and healthy controls. Fractal analysis was employed. STUDY DESIGN Thirty-five individuals (age range 11 to 40 years) who had been diagnosed as having homozygous SCA were enrolled as the patient group. Twenty-six healthy individuals within the same age range constituted the co...
Notch (N) is a receptor for signals that inhibit neural precursor specification [1-6]. As N and its ligand Delta (DI) are expressed homogeneously, other molecules may be differentially expressed or active to permit neural precursor cells to arise intermingled with nonneural cells [7,8]. During Drosophila wing development, the glycosyltransferase encoded by the gene fringe (fng) promotes N signa...
Estrogen stimulates breast development during puberty and mammary tumors in adulthood through estrogen receptor-α (ERα). These effects are proposed to occur via ERα+ luminal cells and not the mammary stem cells (MaSCs) that are ERαneg. Since ERα+ luminal cells express stem cell antigen-1 (SCA-1), we sought to determine if SCA-1 could define an ERα+ subset of EpCAM+/CD24+/CD49fhi MaSCs. We show ...
Measuring similarity is crucial to many learning tasks. To this end, metric learning has been the dominant paradigm. However, similarity is a richer and broader notion than what metrics entail. For example, similarity can arise from the process of aggregating the decisions of multiple latent components, where each latent component compares data in its own way by focusing on a different subset o...
The endosteal niche is critical for the maintenance of hematopoietic stem cells (HSCs). However, it consists of a heterogeneous population in terms of differentiation stage and function. In this study, we characterized endosteal cell populations and examined their ability to maintain HSCs. Bone marrow endosteal cells were subdivided into immature mesenchymal cell-enriched ALCAM(-)Sca-1(+) cells...
Nigeria has the highest population of sickle cell anemia (SCA) patients in the whole world. This condition manifests with frequent episodes of aches and pains, recurrent infections, and frequent hospitalization. Prenatal screening is one of the methods of reducing the prevalence of this disease. The study aimed to determine the awareness and acceptability of prenatal screening for SCA among hea...
Background A seemingly interesting observation in patients with sickle cell anaemia (SCA) is that they usually have lower systemic blood pressures (BP) and insulin resistance than persons in the general population in spite of chronic inflammation and vasculopathy. However, relative systemic hypertension (rHTN) has been linked to pulmonary hypertension, increased blood viscosity and renal insuff...
aigus (SCA) (infarctus aigu du myocarde et angine instable); un aussi grand nombre de patients sont hospitalisés pour que soit finalement «écarté» le diagnostic de SCA. Le diagnostic de SCA doit être rapide et exact afin de réduire le taux de mortalité et de prévenir la progression de l’angine instable vers un infarctus du myocarde. En même temps, on doit limiter les coûts inutiles liés au trai...
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