traumatic brain injury (tbi) is described by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. the use of human stem cells and self-assembling peptide scaffolds suggest huge potential for application in the treatment of tbi. in the present study, we surveyed the beneficial effec...

Biodegradable scaffolds play a critical role in therapeutic tissue engineering, in which the matrix degradation and tissue ingrowth are of particular importance for determining the ongoing performance of tissue-scaffold system during regenerative process. This paper aims to explore the mechanobiological process within biodegradable scaffolds, where the representative volume element (RVE) is ext...

We present here-designed, manufactured, and tested by our research team-the Ti-alloy prototype of the multispiked connecting scaffold (MSC-Scaffold) interfacing the components of resurfacing arthroplasty (RA) endoprostheses with bone. The spikes of the MSC-Scaffold prototype mimic the interdigitations of the articular subchondral bone, which is the natural biostructure interfacing the articular...

This paper introduces a digital safety monitoring device for attached lifting scaffold, including scaffold and control device. The includes point, intermediate station, center, communication converter, display mobile terminal. point is set on the wirelessly connected with station. station transmits data to center through network mapping. respectively converter utility model has simple structure...

Suitable alternatives are made for damaged or diseased organs and tissues in tissue engineering by combining cellular and molecular biology with materials and mechanical engineering. Fibrin is a critical blood component responsible for homeostasis, used extensively as a biopolymer scaffold in tissue engineering. This study summarizes the latest developments in organ and tissue regeneration usin...

Bone tissue engineering implants with sustained local drug delivery provide an opportunity for better postoperative care for bone tumor patients because these implants offer sustained drug release at the tumor site and reduce systemic side effects. A rapid prototyped macroporous polycaprolactone scaffold was embedded with a porous matrix composed of chitosan, nanoclay, and β-tricalcium phosphat...

Combining a nanocomposite technique and the electrospinning process, a robust dual-porosity scaffold structure was developed for a facile transport of metabolic nutrients and wastes through the nano-sized pores and for the cell implantation and blood vessel invasion through the micro-sized pores. The montmorillonite (MMT) nano-sized platelets were incorporated into poly(L-lactic acid) (PLLA) so...

The crystal structure of the scaffolding protein CheW from Thermoanaerobacter tengcongensis (TtCheW) is reported with a resolution at 2.2A using molecular replacement. Based on the crystal structure TmCheA P4-P5-TmCheW from Thermotoga maritime reported by others, we modeled the TmCheA P4-P5-TtCheW complex and predicted that TtCheW is involved in a hydrophobic interaction with CheA, similar to t...

PURPOSE The purpose of this study was to evaluate an application of poly(d,l-lactide-co-glycolide) (PLG) scaffold created by electrospinning in a rabbit rotator cuff defect model. METHODS Forty-two Japanese white rabbits were used in this study. Defects of the infraspinatus tendon were created, and the PLG scaffolds were implanted. Contralateral infraspinatus tendons were reattached without c...