Atopic dermatitis (AD) is a chronic relapsing skin disease, associated with impaired barrier function and characterized by poorly defined pruritic, erythematous lesions. In this study, the efficacy of new topical cream (IALUSET VITAL®), containing hyaluronic acid extract Salvia haenkei, in reducing symptoms moderate AD adults was investigated. This study randomized, double blind, vehicle-contro...

Background. Atopic dermatitis is a common pruritic skin disease that causes significant burden on patients, their families, and society. The purpose of this work was to evaluate the quality life children with atopic study correlation between severity according Children’s Dermatology Life Quality Index (CDLQI). Materials methods. Patients (n = 71) aged 4–17 years from allergy department Kyiv Cit...

Background: Patients with atopic dermatitis (AD) often report sleep disturbance due to nighttime itching and scratching, leading daytime fatigue impaired quality of life. The DUPISTAD phase 4 randomized double-blinded placebo-controlled study (NCT04033367) evaluated the impact dupilumab treatment on in adults moderate-to-severe AD. Methods: Adult patients an Eczema Area Severity Index (EASI) ≥ ...

BACKGROUND Atopic dermatitis (AD) patients may benefit from using textiles coated with skin microbiome-modulating compounds. Chitosan, a natural biopolymer with immunomodulatory and antimicrobial properties, has been considered potentially useful. OBJECTIVE This randomized controlled trial assessed the clinical utility of chitosan-coated garment use in AD. METHODS Of the 102 patients screen...

Background: Recent discovery of the Th17 pathway is providing new opportunities for understanding chronic immune-mediated diseases. The Th17 pathway has been historically associated with chronic inflammatory diseases such as psoriasis, multiple sclerosis, and rheumatoid arthritis. Among Th17 cytokines, pathogenic roles of IL-17A and IL-17F in asthma have been well described. Recently, the numbe...

Atopic dermatitis is one of the most common allergic diseases that almost always respond to conventional therapies with topical emollient, topical corticosteroids, systemic antihistamines and allergic abstinence. However few cases of atopic dermatitis with severe course do not respond to conventional therapies and high dose of intravenous immunoglobulin or cyclosporine are recommended for them....

Multiple treatment modalities, including topical and systemic corticosteroid and phototherapy, have been used in treatment of patients with atopic dermatitis. However, long-term corticosteroid therapy may have various adverse effects. The purpose of this study was to investigate the therapeutic efficacy and safety of bath therapy using green tea extracts for treatment of patients with atopic de...

Empowering heliotherapy aims at clinical healing and improved coping with psoriasis and atopic dermatitis, but evidence of long-term effects is scarce. We studied the effect of 2-week empowering heliotherapy in the Canary Islands on clinical outcome and quality of life in 22 psoriasis and 13 atopic dermatitis patients. Empowerment consisted of meeting peers, sharing experiences and performing p...