OBJECTIVE To examine the distribution of maternal serum placental growth factor (PlGF) at 12, 22, 32 and 36 weeks' gestation in singleton pregnancies which develop pre-eclampsia (PE) and examine the performance of this biomarker in screening for PE. METHODS Serum PlGF was measured in 40 212 cases at 11-13 weeks, in 10 282 cases at 19-24 weeks, in 10 400 at 30-34 weeks and 4043 at 35-37 weeks....

This prospective research analyzed how different facets of perceived self-efficacy operate in concert within a network of sociocognitive influences in childhood depression. Perceived social and academic inefficacy contributed to concurrent and subsequent depression both directly and through their impact on academic achievement, prosocialness, and problem behaviors. In the shorter run, children ...

A new metric for the evaluation of model performance in the field of virtual screening and quantitative structure– activity relationship applications is described. This metric has been termed the power metric and is defined as the fraction of the true positive rate divided by the sum of the true positive and false positive rates, for a given cutoff threshold. The performance of this metric is c...

The recent proliferation of terrestrial and space-based communication systems has given rise to an increasingly critical problem—the lack of available frequency spectrum. One tool that satellite system designers can use to maximize the use of available spectrum is bandwidth-efficient modulation. This technique can enhance bandwidth efficiency while retaining reasonable power efficiency and impl...

The absolute time required to check and repair a file system is increasing because disk capacities are growing faster than disk bandwidth and seek time remains almost unchanged. At the same time, file system repair is becoming more common, because the per–bit error rate of disks is not dropping as fast as the number of bits per disk is growing, resulting in more errors per disk. With existing f...

One in five American children grows up in poverty. Childhood poverty has far-reaching adverse impacts on cognitive, social and emotional development. Altered development of neurocircuits, subserving emotion regulation, is one possible pathway for childhood poverty's ill effects. Children exposed to poverty were followed into young adulthood and then studied using functional brain imaging with a...

This study uses analysis of co-variance in order to determine which cognitive/learning (working memory, knowledge integration, epistemic belief of learning) or social/personality factors (test anxiety, performance-avoidance goals) might account for gender differences in SAT-V, SAT-M, and overall SAT scores. The results revealed that none of the cognitive/learning factors accounted for gender di...

OBJECTIVE To assess the performance of the universal newborn hearing screen in England. DESIGN Retrospective analysis of population screening records. STUDY SAMPLE A total of 4 645 823 children born 1 April 2004 to 31 March 2013. RESULTS 97.5% of the eligible population complete screening by 4/5 weeks of age and 98.9% complete screening by three months of age. The refer rate for the 12/13...

PURPOSE To identify radiologists' characteristics associated with interpretive performance in screening mammography. MATERIALS AND METHODS The study was approved by institutional review boards of University of Washington (Seattle, Wash) and institutions at seven Breast Cancer Surveillance Consortium sites, informed consent was obtained, and procedures were HIPAA compliant. Radiologists who in...

We evaluated the performance characteristics of chromID CARBA and HardyCHROM Carbapenemase for the detection of carbapenemase-producing Enterobacteriaceae (CPE). A CPE prevalence study was conducted using chromID CARBA; this demonstrated that in low-prevalence settings, CPE screening agars may lack specificity, and confirmation of putative isolates is necessary.