Two new norditerpenoid alkaloids, named scutebarbatines M-N (1 and 2), were isolated from the whole plant of Scutellaria barbata D. Don. Their structures were established on the basis of detailed spectral analyses. In vitro, two new compounds showed significant cytotoxic activities against three human cancer lines (HONE-1 nasopharyngeal, KB oral epidermoid carcinoma and HT29 colorectal carcinom...

Four undescribed pyranone derivatives, named ascomycopyrones A–D (1–4), as well one known analogue simplicilopyrone (5) (this is the first study to report absolute configuration), were isolated from endophytic fungus Ascomycota sp. FAE17 derived flowers of Scutellaria formosa. The structures these pyranones identified by comprehensive spectroscopic and MS analyses, configurations determined the...

Although there have been augmented advances in drug discovery, current OA management is inadequate due to the lack of successful therapies proven to be effective in modifying disease progression. For some, the risk outweighs the benefit. As a result, there is a desperate need for safe and efficacious natural alternatives. Here we evaluated a composition from Morus alba, Scutellaria baicalensis,...

OBJECTIVE Scutellaria luteo-caerulea Bornm. & Snit. is one of the species of genus Scutellaria, within the family of the Lamiaceae, that is used for immune system stimulation and antibacterial effects in traditional medicine in Iran. The aims of this study were to analyze essential oils and mineral element contents of leaves of S. luteo-caerulea in flowering stage of development. MATERIALS AN...

Scutellariae radix (SR), also known as Huangqin, is the dried root of Scutellaria baicalensis Georgi (Lamiaceae). It is listed in the Chinese Pharmacopoeia and is one of the most widely used Chinese herbal medicines against bacterial infection of the respiratory and the gastrointestinal tracts. The main components of SR (and of all Scutellaria species) are baicalein, baicalin, and wogonin. Rhin...

Micellar electrokinetic chromatography (MEKC) conditions were developed to analyze the constituents of Scutellariae Radix (SR) and Scutellaria baicalensis roots. Using the MEKC method, the major flavonoid constituents of baicalin, baicalein and wogonin of wild and cultivated S. baicalensis roots were compared. In a preliminary comparison of electropherogram, one special peak was found in a wild...