Dementia describes the loss of brain function that occurs with certain diseases, and which has the potential to affect memory, thinking, language, judgment, and behavior. Most types of dementia involve irreversible neurodegeneration, and Alzheimer's disease (AD) is the most common form. Beyond AD however, there are many other diseases that can lead to dementia including dementia with Lewy bodie...

Print Physics–Astronomy

Thyroid scintigraphy is a method that formed more than 60 years ago and retains its importance for the diagnosis assessment of risk nodular malignancy. The review examines use scintigraphic in functional metabolic goiter. Prerequisites thyroid nodes screening with short-lived 99mTc-pertechnetate are outlined. Information provided on principles preparation pharmacokinetics, as well variants acti...

A Radiopharmaceutical is a radioactive compound used for the diagnosis and treatment of human diseases. Radiopharmaceuticals are among the most highly regulated materials administered to patients because they are controlled both as drugs and as radioactive substances. The use of radiopharmaceuticals for any purpose is governed by regulatory agencies in different countries all over the wor...

This article describes the 30-y history of nuclear medicine in Brazil, including reactors, production of radiopharmaceuticals, and trends.

Copper-64 was produced in large scales and high specific activities in late 1990s’ using compact cyclotrons based by 64Ni(p,n)64Cu reaction and many radiopharmaceuticals developed since then by various groups based on interesting physicochemical and nuclear properties of the radionuclide. The unique emission of beta particles as well as positron particles offers a spectacu...

The construction of the 68Ge/68Ga generator has increased application of radiopharmaceuticals labeled with this isotope in medicine. 68Ga-PET is widely employed in the management of neuroendocrine tumors but favorable chemistry with tri- and tetraaza-ring molecules has opened wide range of 68Ga application in other fields of PET imaging. This review covers the radiopharmaceuticals labeled with ...

Nuclear imaging techniques play a role in the assessment and management of patients with sarcoidosis. A variety of radiopharmaceuticals have been introduced for this purpose since the late 1970s. The present chapter focuses on these radiopharmaceuticals, scintigraphic imaging techniques, and their role and clinical value in sarcoidosis. Correlation with other imaging modalities, biochemical par...