Since historical times, hysteria has colored the literature from novels to movies. The nomenclature changed from hysteria to dissociation over time. With More reliable diagnostic tools being available it became easier to objectively identify this phenomenon. However clinical examination still appears to be the sole diagnostic approach due to ambiguity in results of widely used investigations li...

PURPOSE To study the development of epilepsy following hypoxia-induced neonatal seizures in Long-Evans rats and to establish the presence of spontaneous seizures in this model of early life seizures. METHODS Long-Evans rat pups were subjected to hypoxia-induced neonatal seizures at postnatal day 10 (P10). Epidural cortical electroencephalography (EEG) and hippocampal depth electrodes were use...

OBJECTIVE To evaluate the effects of sleep on partial seizures arising from various brain regions. METHODS The authors prospectively studied 133 patients with localization-related epilepsy undergoing video-EEG monitoring over a 2-year period. Seizure type, site of onset, sleep/wake state at onset, duration, and epilepsy syndrome diagnosis were recorded. Periorbital, chin EMG, and scalp/spheno...

Epilepsy is a neurological disease arising from abnormal and uncontrollable electrical firings of a group of neurons appearing in the central nervous system. Experimental epilepsy models have been developed to assess the pathophysiology of epileptic seizures and to search for new effective anti-epileptic drugs. This chapter is designed to describe characteristics of experimental epilepsy models...

Early detection of seizures could reduce associated morbidity and mortality and improve the quality of life of patients with epilepsy. In this study, the aim was to investigate whether ictal tachycardia is present in focal and generalized epileptic seizures in children. We sought to predict in which type of seizures tachycardia can be identified before actual seizure onset. Electrocardiogram se...

BackgroundAbout 15 to 40% of children with seizures are refractory to standard anti-epileptic drugs and for such patients, other treatments such as surgery and the ketogenic diet can reduce seizure frequency. Melatonin is a natural pineal gland hormone. The use of melatonin for controlling pediatric seizures is still controversial. This study aimed to evaluate the effect of melatonin on seizure...

objective midazolam is a significant and effective drug for control of a life-threatening condition, generalized and partial refractory convulsive status epilepticus. the goal of this study was evaluation of midazolam efficacy for management of this serious disease and its two side effects, hypotension and respiratory failure. materials & methods our study was done using a quasi experimental me...

The occurrence of de novo psychogenic seizures after epilepsy surgery is rare, and is estimated in 1.8% to 3.6%. Seizures after epilepsy surgery should be carefully evaluated, and de novo psychogenic seizures should be considered especially when there is a change in the ictal semiology. We report a patient with de novo psychogenic seizures after anterior temporal lobe removal for refractory tem...

Dyke-Davidoff-Masson Syndrome (DDMS) is a rare syndrome characterized with specific clinical and radiological findings due to involvement of the developing brain cerebral hemiatrophy one hemisphere. The was first described from Dyke, Davidoff Masson in 1933 series nine patients. has two forms, congenital acquired forms etiological factors vary brain. Most common symptom are focal or secondary g...

OBJECTIVE To evaluate the effects of a daily patient reminder on seizure documentation accuracy. DESIGN Randomized controlled trial. SETTING Monitoring unit of an academic department of epileptology. Patients Consecutive sample of 91 adult inpatients with focal epilepsies undergoing video-electroencephalographic monitoring. Intervention While all patients were asked to document seizures at ...