Background: Poor response to various vaccines especially hepatitis B is common. The purpose of this study was to evaluate the effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients. Methods: In this randomized clinical trial study, 62 insulin dependent diabetic patients were divided into case and control groups (...

Pregnant women and infants are at risk for selenium deficiency, which is known to have negative effects on immune and brain function. We have investigated selenium levels in 158 healthy never-pregnant women and in 114 pregnant and lactating women and their infants at age 6 months and related this to clinical outcomes during the first 6 months of life. Neurodevelopment was assessed with the pare...

BACKGROUND/OBJECTIVES Significant changes have been reported in dietary habits and food availability in Iceland that would be expected to compromise selenium intake and status, especially among young people. These include substantial decreases in the consumption of fish and milk, as well as the selenium content of imported wheat. The aim of this study was to assess selenium in the diet and whol...

An interaction between dietary cobalt and selenium was revealed when groups of female weanling rats were fed standard rations, containing different concentrations and ratios of the two trace elements, continuously over a 15 week period. It was found that the levels of selenium in the heart and skeletal muscle were positively related to dietary selenium and negatively related to dietary cobalt, ...

Present study was conducted to investigate the effect of organic selenium and vitamin E on physico-chemical characteristics of broiler meat. This study was a 3 x 2 factorial arrangement of three levels of organic selenium (0, 0.1, and 0.2 ppm) and two levels of vitamin-E (0 and 300mg/kg). Day-old Vencobb broiler chicks (n=180), were randomly assigned in 6 treatment groups. The experiment lasted...

BACKGROUND Poor response to various vaccines especially hepatitis B is common. The purpose of this study was to evaluate the effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients. METHODS In this randomized clinical trial study, 62 insulin dependent diabetic patients were divided into case and control groups (...

OBJECTIVE To estimate serum zinc and selenium levels in a group of healthy subjects and correlate these with epileptic patients. METHODS This case-control study was conducted in the Department of Neurology, Valiasr Hospital, Iran, between November 2011 and May 2012 on 40 patients aged 26.63+/-5.78 years who were diagnosed with generalized and a single epileptic form of epilepsy by a neurologi...

Selenium deficiency has been reported to result in an extraordinary decrease of glutathione peroxidase (GSH-Px) and, reversely, an increase of detoxifying enzymes such as glutathione-S-transferase (GST), uridine-5'-diphosphate glucuronosyltransferase (UGT), nicotinamide-dependent quinine oxidoreductase (NQO1; DT-diaphorase), and epoxide hydrolase without significantly affecting cytochrome P450 ...

BACKGROUND Selenium is an important trace element for human health. Although numerous epidemiological and interventional studies have examined the association between selenium and diabetes, their findings have been inconclusive. Moreover, no research has specifically focused on the association between dietary selenium and diabetes in the Asian population. The objective of this study was to eval...