Vitamin K antagonists, such as warfarin, have been the mainstay of oral anticoagulation for many decades. Although effective, warfarin has numerous limitations, including a variable dose requirement from patient to patient because of differences in dietary vitamin K intake, common genetic polymorphisms, and multiple drug interactions that affect its pharmacodynamics and metabolism. Consequently...

For the first time in 50 years new oral anticoagulants of proven efficacy and with acceptable safety profiles are available for patients with atrial fibrillation and venous thromboembolism. Here is a brief overview of the benefits and possible disadvantages of using these drugs.

The notion of semi-direct product Poisson $G$-spaces is applied to illuminate examples arising in spin-extensions Ruijsenaars models.

exposure to welding gases can cause health adverse effects. risk assessment is a useful tool for good assessment of exposed workers. the purpose of this study was to determine the risk levels for exposed welders to welding gases. welders (n=239) were selected from iranian natural gas transmission pipelines industry from four regions in iran including assaluyeh, omidieh, loshan, and borujen. ozo...

Ventilator-Associated Pneumonia (VAP) is a type of nosocomial infection that mostly occurs in intensive care units, generally occurring 48 hours after intubation. Endotracheal intubation and the use mechanical ventilator are invasive measures by patients, having therapeutic effect. This paper aimed to identify oral hygiene materials for incidence pneumonia related ventilator. The research desig...

Objective To gather accurate data on the daily mouth care provided in care homes including tooth brushing, oral health assessment, and recording of care provided. Basic research design Direct observation and notes review. Clinical setting Both nursing and 'regular' care homes. Participants 365 Residents living in 16 care homes and their carers underwent observation, notes review or data c...