The transactional memory programming paradigm is gaining momentum as the approach of choice for replacing locks in concurrent programming. This paper introduces the transactional locking II (TL2) algorithm, a software transactional memory (STM) algorithm based on a combination of commit-time locking and a novel global version-clock based validation technique. TL2 improves on state-of-the-art ST...

The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the establishment of a unique resource for dissecting the genetic basis of simple and complex mammalian traits. Toward this end, we present a comprehensive radiation hybrid map of the canine genome composed of 3,...

Absolute genetic differences between neoplastic and nonneoplastic cells can be discerned at sites of homozygous deletions. These deletions are of critical interest because they might be useful in the identification of defective biochemical pathways in neoplastic cells, and subsequently for the development of new treatment strategies in human cancer. We identified an area at 18q21.1 involved by ...

The full-genome sequences of fourteen isolates of Broad bean wilt virus 2 (BBWV2), collected from broad bean, pea, spinach, bell pepper and paprika plants in Korea during the years 2006-2012, were determined and analyzed comparatively along with fifteen previously reported BBWV2 genome sequences. Sequence analyses showed that RNA-1 and RNA-2 sequences of BBWV2 Korean isolates consisted of 5950-...

The Sequence Alignment problem is motivated in part by computational biology. One of the goals of scientists in this field is to determine an evolutionary tree of species by examining how close the DNA is between two potential evolutionary relatives. Doing so involves answering questions of the form “how hard would it be for a species with DNA ‘AATCAGCTT’ to mutate into a species with DNA ‘ATCT...

Nucleic acid-based biochemical assays are crucial to modern biology. Key applications, such as detection of bacterial, viral and fungal pathogens, require detailed knowledge of assay sensitivity and specificity to obtain reliable results. Improved methods to predict assay performance are needed for exploiting the exponentially growing amount of DNA sequence data and for reducing the experimenta...

As vertebrate genome sequences near completion and research refocuses to their analysis, the issue of effective genome annotation display becomes critical. A mature web tool for rapid and reliable display of any requested portion of the genome at any scale, together with several dozen aligned annotation tracks, is provided at http://genome.ucsc.edu. This browser displays assembly contigs and ga...

Development of microsatellite markers has been an increasing trend in crop genetic studies because oftheir applicability in breeding programs. Here we report the development of inter simple sequencerepeat (SSRs) in pomegranate (Punica granatum L.) using an enrichment method that makes use of magneticbeads. Enriched genomic libraries with AG and ATG microsatellite motifs were c...

Limiting the serum protein fouling is a major challenge in design of nanoparticles (NPs) for nanomedicine applications. Suitable chemical surface modification strategies allow to limit interactions with adsorbing proteins. In this communication, we address potential isobutyramide (IBAM) groups grafted on stellate silica (STMS) immobilization two biocompatible polymers renown biomedical and low ...

This technical memo provides a syntactic and semantic basis for state transition diagrams (STDs) as they are used for the description of state transition machines (STMs) with input and output. STMs serve for the specification of system components. We work with STDs with transition rules labelled by input and output patterns and preand postconditions. We extend our notation to support specificat...