Mixed ligand complexes of bivalent metal ions, viz; Co(II), Ni(II), Cu(II) and Zn(II) of the composition (ML1L2) in 1:1:1 molar ratio, (where L1=diphenylamine-2-mercapto-2’-carboxylic acid (DPMC) and L2=2-furyl glyoxalanthranilic acid (FGAA) have been synthesized and characterized by repeated melting point determination, elemental analyses, IR, H-NMR, magnetic susceptibility measurements and el...

Dispensing and dilution processes may profoundly influence estimates of biological activity of compounds. Published data show Ephrin type-B receptor 4 IC50 values obtained via tip-based serial dilution and dispensing versus acoustic dispensing with direct dilution differ by orders of magnitude with no correlation or ranking of datasets. We generated computational 3D pharmacophores based on data...

In vitro antimicrobial activity of seventeen heterocyclic nitrogen compounds {2-substituted pyrido [1,2-a] pyrimidin -4-oxo-1 [4]-3-Carbonitriles and ethyl 5-amino-3-(substituted) - pyrazole-3-Carboxylates} was tested against Escherichia coli, Bacillus subtilis and candida albicans strains, Antimicrobial activity was measured using standard two -fold serial dilution method and the minimum inhib...

An automated, quantitative microhemagglutination assay for antibodies to Treponema pallidum was developed by using T. pallidum-sensitized erythrocytes and an automatic serial-dilution instrument. Reactivity was found in sera from 54 rabbits and 6 chimpanzees infected with T. pallidum. Reactivity was also found in sera from animals infected with T. pertenue, T. carateum, and T. cuniculi. No reac...

What is homeopathy? Homeopathy is a complete system of medical treatment that makes use of substances normally found in nature, which are prepared into remedies by a process of serial dilution. In use for over two centuries, it continues to be an effective means of curing disease and palliating incurable illnesses. Homeopathy makes use of plants, minerals and animal derivatives, although the so...

S KIN testing is one of the basic investigative procedures used by most allergists. The preference for any one test varies great.ly among the different workers. Four different tests were evaluated in this study: puncture, intracutaneous, conjunctival, and serial dilution intracutaneous threshold test. There was a total of 215 patients who were clinically sensitive to ragweed or grass pollens. T...

The in vitro activity of chephaloridine, cephalexin, cefatrizine (BL-S640), and cephapirin (BL-P-1322) was evaluated by the serial dilution method against pathogenic gram-positive and gram-negative bacteria isolated from bovine udders and neonatal calf diseases. Cephapirin showed the comparatively greatest activity against the most common streptococcal species associated with bovine mastitis, w...

A new class of quinoline derivatives containing pyrazoline-5-one and pyrazole moiety (3a-j and 4a-j) have been synthesized by condensation of various oxobutyrates/pentane-2,4-dione derivatives with 8-quinolinoxyacetic acid hydrazide. Elemental analysis, IR, H NMR and mass spectral data support the structures of the newly synthesized compounds. The synthesized compounds have been evaluated for t...

The main objective of this study is to identify the most suitable herbal plants for removing contaminants reduce use chemicals water contamination. microbial studies were performed in contaminated kitchen and household wastewater treated (with various medicinal plants, i.e., Azardichta Indica, Ocimum tenuiflorum, Pinus roxburghii) using serial dilution method. Aqueous extracts dried powdered pl...