BACKGROUND Glycophorin variants of the MNSs blood group are important in Taiwan. For more than 20 years, screening for the most frequent irregular antibody, anti-''Mi(a)', has been conducted by using 'Mi(a)'(+) RBCs, with a significant success. However, the sensitivity and the specificity of this screening strategy have never been validated, and the true incidences of different glycophorin vari...

methods: in a retrospective descriptive study, medical records of 204 hip fractured patients with the age of 60 or older who were admitted to the department of orthopedics was considered regarding routine laboratory tests. predictive values of these tests were assessed using receiver operating characteristic curve (roc).  results: the incidence of death due to hip fracture was 24%. the mortalit...

Chronic HCV infection, a highly endemic disease in Egypt, is usually asymptomatic for decades after infection. Prediction questionnaire tool was proofed to be a valuable, feasible and efficient instrument for the screening of several diseases. We previously developed an Egyptian HCV risk screening tool (EGCRISC). This study aims to validate/modify EGCRISC. A cross-sectional study testing 4579 i...

the aim of this study was to determine the diagnostic value of a serologic test for helicobacter pylori (h. pylori) in pediatric population presenting with abdominal pain suspected of peptic disease. we conducted a preospective cross sectional study. there were 202 children with abdominal pain. serologic bm test using helisual quick test kit was performed. all patients then underwent endoscopic...

and commercial kits (3). Future availability of promising ultra-sensitive tests (e.g., PCR and antigenic tests) may overcome the limitations associated with conventional microscopy and serologic testing for low-parasite load schistosomiasis. As stated in our manuscript, we cannot exclude the possibility that our case definition generated false-positives; the potential limitations of our finding...

A panel of seven recombinant antigens, derived from Ehrlichia phagocytophila (the agent of human granulocytic ehrlichiosis), was evaluated by class-specific enzyme-linked immunosorbent assays (ELISAs) for utility in the diagnosis of the infection. Fourteen genomic fragments, obtained by serologic expression screening, contained open reading frames (ORFs) encoding 16 immunodominant antigens. Ele...

CONTEXT The correct diagnosis of celiac disease in environmentally deprived children is frequently hindered by the common presence of other causes for the classical celiac disease symptoms: malnutrition, failure to thrive and frequent diarrheas. OBJECTIVES To determine the prevalence of celiac disease in a group of 12 to 36 month-old children using immunoglobulin antibodies against gliadin (I...

BACKGROUND This multicenter prospective study was designed to evaluate the performance characteristics of a new commercially available enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to Trypanosoma cruzi in blood donors, the ORTHO T. cruzi ELISA Test System (Ortho-Clinical Diagnostics). STUDY DESIGN AND METHODS Assay specificity was evaluated among 40,665 serum and e...

BACKGROUND The purpose of this study was to estimate the cost-effectiveness of using individual-donor nucleic acid testing (ID-NAT) in addition to serologic tests compared with the sole use of serologic tests for the identification of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) among blood donors in Sweden. STUDY DESIGN AND METHODS The two strategi...