نتایج جستجو برای: serotonergic system
تعداد نتایج: 2235328 فیلتر نتایج به سال:
in the present study, we have investigated the effects of silymarine on depression and the possible role of serotonergic system in these effects. the rats were anesthetized intraperitoneally with ketamine hydrochloride and placed in a stoelting stereotaxic instrument. a stainless steel guide cannula (22-gauge) was implanted in the third ventricular region. the third ventricular region was infus...
Opioids remain the most effective analgesics despite their potential adverse effects such as tolerance and addiction. Mechanisms underlying these opiate-mediated processes remain the subject of much debate. Here we describe opioid-induced behaviors of Lmx1b conditional knockout mice (Lmx1bf/f/p), which lack central serotonergic neurons, and we report that opioid analgesia is differentially depe...
Agonistic aggression has provided an excellent framework to study how conserved circuits and neurochemical mediators control species-specific and context-dependent behavior. The principal inhibitory control upon aggression is serotonin (5-HT) dependent, and the activation of 5-HT(1A) receptors is involved in its action. To address whether the serotonergic system differentially regulates differe...
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