Background: Neonatal Jaundice is a common problem that occurs in most preterm and term neonates. This systematic review aimed to examine the evidence for the effects of oxytocin in labor on neonatal jaundice. Materials and Methods: In this systematic review study, English databases including PubMed, Google Scholar, Embase, Cochrane Library, Scopus, Web of Sciences, and Persian databases includi...

One aim of laboratory investigation in neonatal jaundice is to prevent kernicterus from occurring. Estimation of the bilirubin-binding capacity of serum is an important measurement along with total bilirubin determination. With a convenient Sephadex competitive binding procedure, KERNLUTE provides information on whether or not the neonate's bilirubin-binding capacity has been exceeded. Further ...

OBJECTIVE In this study, we determined the assay performance criteria necessary to produce acceptable results for >or=98% of neonate bilirubin samples collected by capillary heel-stick. STUDY DESIGN AND METHODS We determined serum free hemoglobin levels in 151 heel-stick serum samples to determine the hemolysis level. We then tested the effect of hemolysis on total bilirubin levels determined...

Carswell, F., Kerr, M. M., and Dunsmore, I. R. (1972). Archives of Disease in Childhood, 47, 021. Sequential trial of effect of phenobarbitone on serum bilirubin of preterm infants. (1) Phenobarbitone in a dose of 8 mg/kg per day was given in twice-daily intramuscular doses to preterm infants with a gestational age of 36 completed weeks or less. The phenobarbitone was started within the first 2...

Background: Neonatal jaundice is clinically presented in 60% of full-term newborns. About 8% of newborns with jaundice have urinary tract infection (UTI) without any other clinical signs in favor of UTI. In present study we evaluated clinical and paraclinical data that help to rapid and early diagnosis of UTI in apparently healthy newborns with jaundice. Methods: From February to August 2006, 5...

BACKGROUND Bilirubin has been recognized as an anti-oxidant. The purpose of this study was to examine whether bilirubin would act as an antioxidant for surgical stress in humans. MATERIALS AND METHODS Serum bilirubin and urinary bilirubin oxidative metabolites (BOM) were measured in 96 patients who underwent surgery. The antioxidant activity of bilirubin was assessed using BOM measured by enz...

Increased plasma levels of bilirubin have been reported in rat models and patients with alcoholic liver disease (ALD). The constitutive androstane receptor (CAR) is a known xenobiotic receptor, which induces the detoxification and transport of bilirubin. In the present study, the bilirubin transport regulatory mechanisms, and the role of CAR activation in hepatic and extrahepatic bilirubin clea...

BACKGROUND The association of serum bilirubin concentrations with kidney function and albuminuria has not been established in the US general population. METHODS We performed a cross-sectional analysis of data from the National Health and Nutrition Examination Survey (NHANES) 2001-2006 and examined the associations of serum total bilirubin concentrations with estimated glomerular filtration ra...

Background: There is risk of developing bilirubin encephalopathy (kernicterus) in cases in which early diagnosis and treatment of high bilirubin levels are not available. The follow-up and treatment of neonatal indirect hyperbilirubinemia are, therefore, important. Aim: This study was conducted to evaluate the relationship between serum bilirubin levels and the frequency of urination and stooli...