Parkinson’s Disease (PD) is a chronic, progressive, neurodegenerative disorder with motor and non-motor signs and symptoms. PD is caused by idiopathic degeneration of dopamine-producing cells in the substantia nigra, located in the midbrain. Recently, Trace elements have been recognized to play an important role in the development of Parkinson’s disease (PD). The aim of this review ...

This study was to determine the feasibility of using potentiometric stripping analysis (PSA) to measure serum levels of copper, lead, and zinc in elderly subjects with metabolic disorders (hyperglycemia, hypertriglyceridemia, and hypercholesterolemia). Furthermore, we investigated the relationship between serum trace elements and lipid and glucose levels in these patients. There was a strong co...

The serum concentrations of zinc and copper were measured in 50 patients with multiple sclerosis. Lower serum zinc levels were found compared to age- and sex-matched controls. In younger patients low serum copper concentrations were noted. Zinc concentrations in CSF were unchanged. The possibility that malabsorption of the metals causes the low serum concentrations is discussed.

OBJECTIVE To determine the efficacy of oral zinc for treatment of idiopathic neonatal hyperbilirubinemia in near-term and term (35-41 weeks) neonates. DESIGN Randomized placebo-controlled trial. SETTING Tertiary-care teaching hospital. PARTICIPANTS Eighty newborns with idiopathic neonatal hyperbilirubinemia. INTERVENTION Neonates were randomized to receive either oral zinc sulfate (10 m...

INTRODUCTION Despite great advances in the management of diarrhoeal diseases, persistent diarrhoea remains a major problem in developing countries due to its syndromic nature. Zinc depletion ranks high among the factors contributing to the detrimental effects of persistent diarrhoea on the human body. This however, has not been investigated in the Ugandan population. OBJECTIVE To determine th...

BACKGROUND Hyperglycemia and gestational diabetes mellitus are complications of pregnancy. Both mothers and newborns are typically at increased risk for complications. This study sought to determine effect of zinc supplementation on serum glucose levels, insulin resistance, energy and macronutrients intakes in pregnant women with impaired glucose tolerance. METHODS In this clinical trial 44 p...

Zinc deficiency is prevalent throughout the world, including the USA. Severe and moderate deficiency of zinc is associated with hypogonadism in men. However, the effect of marginal zinc deficiency on serum testosterone concentration is not known. We studied the relationship between cellular zinc concentrations and serum testosterone cross-sectionally in 40 normal men, 20 to 80 y of age. In four...