نتایج جستجو برای: severe traumatic brain injury

تعداد نتایج: 1057182  

2010
Arshad Ali Khan Ashis Banerjee

BACKGROUND Post-traumatic seizures cause secondary brain injury, contributing to morbidity and mortality after traumatic brain injury. Seizure activity may be undetectable if the patient is paralysed and ventilated. AIMS The effect of prophylactic anticonvulsant therapy on the prevention of seizures after moderate to severe traumatic brain injury was studied. METHODS A structured systematic...

2015
Alistair Nichol Craig French Lorraine Little Jeffrey Presneill D James Cooper Samir Haddad Jacques Duranteau Olivier Huet Markus Skrifvars Yaseen Arabi Rinaldo Bellomo

BACKGROUND Traumatic brain injury is a leading cause of death and disability worldwide. Laboratory and clinical studies demonstrate a possible beneficial effect of erythropoietin in improving outcomes in the traumatic brain injury cohort. However, there are concerns regarding the association of erythropoietin and thrombosis in the critically ill. A large-scale, multi-centre, blinded, parallel-g...

Journal: :Free radical biology & medicine 2014
Valentina Di Pietro Giacomo Lazzarino Angela Maria Amorini Barbara Tavazzi Serafina D'Urso Salvatore Longo Roberto Vagnozzi Stefano Signoretti Elisabetta Clementi Bruno Giardina Giuseppe Lazzarino Antonio Belli

Neuroglobin is a neuron-specific hexacoordinated globin capable of binding various ligands, including O2, NO, and CO, the biological function of which is still uncertain. Various studies seem to indicate that neuroglobin is a neuroprotective agent when overexpressed, acting as a potent inhibitor of oxidative and nitrosative stress. In this study, we evaluated the pathophysiological response of ...

Journal: :Annual review of pathology 2016
Jennifer Hay Victoria E Johnson Douglas H Smith William Stewart

Almost a century ago, the first clinical account of the punch-drunk syndrome emerged, describing chronic neurological and neuropsychiatric sequelae occurring in former boxers. Thereafter, throughout the twentieth century, further reports added to our understanding of the neuropathological consequences of a career in boxing, leading to descriptions of a distinct neurodegenerative pathology, term...

Journal: :archives of trauma research 0
sharhokh yousefzadeh-chabok neurosurgery department, guilan road trauma research center, guilan university of medical sciences, rasht, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (guilan university of medical sciences) anoush dehnadi moghaddam anesthesiology department, guilan road trauma research center, guilan university of medical sciences, rasht, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (guilan university of medical sciences) ehsan kazemnejad-leili biostatistics department,guilan road trauma research center, guilan university of medical sciences, rasht, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (guilan university of medical sciences) zahra saneei guilan road trauma research center, guilan university of medical sciences, rasht, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (guilan university of medical sciences) marieh hosseinpour guilan road trauma research center, guilan university of medical sciences, rasht, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (guilan university of medical sciences) leila kouchakinejad-eramsadati human resource management, guilan road trauma research center, guilan university of medical sciences, rasht, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (guilan university of medical sciences)

conclusions increased serum levels of interleukins 6 and 8 as a predictive marker might be associated with unfavorable clinical outcome in patients with severe tbi. results comparing the serum levels of interleukins in two groups with favorable and unfavorable clinical outcomes showed that the mean serum levels of interleukins 6 and 8 in group with favorable outcome was 85.2 ± 51.6 and 52.2 ± 3...

Journal: :Journal of Trauma and Acute Care Surgery 2013

Journal: :Pediatric Critical Care Medicine 2017

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