BACKGROUND Bacteria produce small molecule iron chelators, known as siderophores, to facilitate the acquisition of iron from the environment. The synthesis of more than one siderophore and the production of multiple siderophore uptake systems by a single bacterial species are common place. The selective advantages conferred by the multiplicity of siderophore synthesis remains poorly understood....

abstract fluorescens pseudomonads can suppress soil-borne plant pathogens by employing several mechanisms such as competition for iron by means of siderophores. three indigenous strains pseudomonas fluorescens (utpf5, utpf61 and utpf76), pseudomonas aeruginosa 7nsk2 and its pyoverdin mutant, mpfm1, were used for investigation the effect of iron competition on bean damping-off suppression. the r...

Since the ban on use of asbestos due to its carcinogenic properties, removal cement, representing major asbestos-containing waste, has proven be a challenge in most industrial countries. Asbestos-containing products are mainly disposed landfills and have remained untreated. Bioremediation involving bacteria previously reported ability Pseudomonas aeruginosa release iron from flocking waste thro...

Iron is essential for nearly all biological events. Siderophores are indispensable for most organisms to obtain iron from iron-limiting milieus. This holds particularly true for pathogens such as the causative agent of tuberculosis - Mycobacterium tuberculosis. The categories of mycobacterial siderophores, their biosynthesis and regulation are summarized here. The siderophore biosynthesis and r...

Rootlet elongation and bacterial growth on rootlets were determined after inoculation of cucumber and spinach seedlings with Pseudomonas strains differing in production of siderophores and HCN. Siderophore producers grew more profusely than nonproducers on both species and promoted rootlet elongation on cucumber. Coinoculation of siderophore producers and nonproducers resulted in restricted gro...

Preliminary enthusiasm over the encouraging spectrum and in vitro activities of siderophore conjugates, such as MB-1, was recently tempered by unexpected variability in in vivo efficacy. The need for these conjugates to compete for iron with endogenously produced siderophores has exposed a significant liability for this novel antibacterial strategy. Here, we have exploited dependence on efflux ...

Abstract Siderophores are strong iron‐binding molecules produced and utilized by microbes to acquire the limiting nutrient iron (Fe) from their surroundings. Despite importance as a component of ligand pool in seawater, data on distribution siderophores that use them limited. Here, we measured concentrations types dissolved during two cruises April 2016 June 2017 transited iron‐replete, low‐mac...

Siderophores are iron-chelating low-molecular-weight compounds that bind iron (Fe3+) with a high affinity for transport into the cell. The newly isolated strain Streptomyces tricolor HM10 secretes pattern of secondary metabolites. Siderophore molecules representatives such S. produces catechol, hydroxamate, and carboxylate types siderophores. Under 20 ?M FeCl3 conditions, produced up to 6.00 µg...

Bacterial siderophores are a group of chemically diverse, virulence-associated secondary metabolites whose expression exerts metabolic costs. A combined bacterial genetic and metabolomic approach revealed differential metabolomic impacts associated with biosynthesis of different siderophore structural families. Despite myriad genetic differences, the metabolome of a cheater mutant lacking a sin...

Bacteria produce a great diversity of siderophores to scavenge for iron in their environment. We suggest that this diversity results from the interplay between siderophore producers (cooperators) and non-producers (cheaters): when there are many cheaters exploiting a siderophore type it is beneficial for a mutant to produce a siderophore unusable by the dominant population. We formulated and an...