OBJECTIVES To assess the efficacy and factors associated with successful treatment of sildenafil citrate for erectile dysfunction after radical prostatectomy (RP). METHODS Of the 470 patients who underwent RP at our institution between July 1998 and January 2000, 227 (48%) sought treatment for erectile dysfunction, and 174 (37%) were prescribed sildenafil citrate. The starting dose was 50 mg,...

We aimed to investigate the effect of adding sildenafil vaginal gel to clomiphene citrate (CC) in infertile women with prior CC failure. METHODS This is a self- controlled clinical trial. Women with CC failure (in prior 5 cycles) and thin endometrium were recruited (N = 42). In their 6th (CC only) cycle, women continued on CC 100 mg/ day for 5 days, and had measurement of endometrial thicknes...

The aim of the investigation described here was to examine the differences between genuine and counterfeit pharmaceutical products through the development of an analytical method capable of rigorously identifying the sugar-based excipients. High Performance Anion Exchange Chromatography, coupled to Pulsed Amperometric Detection (HPAEC-PAD), supported by Gas Chromatography-Mass Spectrometry (GC-...

BACKGROUND Endometrial development has an important role in blastocyst adhesion and implantation. During IVF cycles, endometrial development is enhanced by progesterone. OBJECTIVE The aim of this study was to compare ultrastructural and morphometrical characteristics of mice uterine endometrium in natural cycle with those in superovulated cycles received progesterone or Sildenafil. MATERIAL...

INTRODUCTION Erectile dysfunction (ED) can significantly impact a man's relationships and well-being. AIM We assessed changes in self-esteem, confidence, sexual relationship satisfaction, and overall relationship satisfaction in men with ED using the validated Self-Esteem And Relationship questionnaire (SEAR). METHODS This was a 12-week, double-blind, placebo-controlled, flexible-dose (25, ...

A simple, quick, accurate, and sensitive colorimetric method is described for the determination of sildenafil citrate (SLD). The method is based on the reaction of SLD with Congo Red, Sudan II, and Gentian Violet in buffered aqueous solutions at pH 2.5, 6.5, and 11.0, respectively, to give highly colored soluble ion-associate complex species; the colored products are quantitated colorimetricall...

The aim of the investigation described here was to examine the differences between genuine and counterfeit pharmaceutical products through the development of an analytical method capable of rigorously identifying the sugar-based excipients. High Performance Anion Exchange Chromatography, coupled to Pulsed Amperometric Detection (HPAEC-PAD), supported by Gas Chromatography-Mass Spectrometry (GC-...

INTRODUCTION The physiological changes that occur in menopause alter sexual function and affect well-being. Hormonal changes contribute significantly to reduced sexual function in older women and sexual dysfunction may well be amenable to treatment with exogenous hormones or other agents. MATERIALS AND METHODS Relevant clinical studies were identified by a computerised literature search. The ...

Spices are considered as sexual invigorators in the Unani System of Medicine. In order to explore the sexual function improving effect of Semecarpus anacardium an experimental study was conducted in normal male mice. The chloroform extract of Semecarpus anacardium was administered (150 mg/kg & 300 mg/kg; p.o.) to different groups of male Mice. Mounting behavior & mating performance were determi...