PURPOSE To characterize various properties of a physiologically-relevant artificial tear solution (ATS) containing a range of tear film components within a complex salt solution, and to measure contact lens parameters and lipid deposition of a variety of contact lens materials after incubation in this ATS. METHODS A complex ATS was developed that contains a range of salts, proteins, lipids, m...

purpose: to evaluate corneal thickness changes after soft contact lens (scl) removal in lasik candidates. methods: fifty lasik candidates (100 eyes) with history of daily wear scl for at least 6 months were enrolled in this descriptive study. central corneal thickness was measured by ultrasonic pachymetry immediately after lens removal and then repeated daily at the same time, until the thickne...

acanthamoeba keratitis is a vision- threatening infection and the most important risk factors are contact lenses characteristic symptoms include disproportionately severe ocular pain, epithelial ulcer, ring stromal infiltrate and resistance to antimicrobial treatment. the aim is to report the first cases of acanthamoeba keratitis in yazd in a retrospective study confirmed on histopathological a...

Fifty conjunctival swab samples collected from ELISA confirmed HIV/AIDS seropositive patients who were referred to the HIV/AIDS laboratories of the University of Benin Teaching Hospital and Central Hospital both based in Benin City, Nigeria were aseptically cultured on appropriate media by standard methods. The resulting isolates/strains, after identification by standard methods, were tested fo...

PURPOSE An in vitro study was conducted to measure the adsorption of major tear film lipids to soft contact lenses over time. METHODS Commercial balafilcon A (PureVision; Bausch & Lomb, Rochester, NY), galyfilcon A (Acuvue Advance; Johnson & Johnson Vision Care), lotrafilcon A and B (Night & Day And O(2)Optix; CIBA Vision, Duluth, GA), senofilcon A (Acuvue Oasys; Johnson & Johnson Vision Care...

The amount of initial corneal swelling and the time course of corneal deswelling were measured after overnight wear of several types of hard and hydrogel lenses. Deswelling occurred in the right eye with the lens still on the cornea. In the left eye the lens was removed at eye opening and left off the cornea during deswelling. For lenses of equal nominal oxygen transmissibility, hard lenses ini...

Aim: To evaluate the compatibility of poloxamer hydrogel as a material for an injectable intraocular lens, in vivo and in vitro. Methods: The appropriate concentration of poloxamer hydrogel was determined for injection by examining the transparency and gelling temperature of this material, assessing the lens capsule refilling technique, and studying the postoperative findings in a rabbit model....

AIM To evaluate the compatibility of poloxamer hydrogel as a material for an injectable intraocular lens, in vivo and in vitro. METHODS The appropriate concentration of poloxamer hydrogel was determined for injection by examining the transparency and gelling temperature of this material, assessing the lens capsule refilling technique, and studying the postoperative findings in a rabbit model....

We numerically demonstrated the characteristics of a functional hydrogel layer on a silicon-based grating waveguide for a simple, cost-effective refractive index (RI) biochemical sensor. The RI of the functional hydrogel layer changes when a specific biochemical interaction occurs between the hydrogel-linked receptors and injected ligand molecules. The transmission spectral profile of the grati...

Many biological interfaces provide low friction aqueous lubrication through the generation and maintenance of a high water content polymeric surface gel. The lubricity of such gels is often attributed to their high water content, high water permeability, low elastic modulus, and their ability to promote a water film at the sliding interface. Such biological systems are frequently characterized ...