PURPOSE Recent studies have found that S100B is a useful marker for astroglial activation seen in various neurologic disorders. The purpose of this study was to evaluate whether simple febrile seizures (SFS) was associated with an elevation in serum S100B levels. METHODS In this study the samples consisted of 39 patients with SFS ranging from 6 to 36 months of age, and age-matched and sex-mat...

OBJECTIVE Recognition of risk factors for febrile seizures (FS) and epilepsy is essential. Studies regarding the role of melatonin in these convulsive disorders are limited. This study determines the relationship between serum melatonin levels and FS and epilepsy in children. MATERIALS & METHODS A population of 111 children with simple FS, complex FS, and epilepsy (37 children per group, resp...

Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and mesial temporal lobe epilepsy with hippocampal sclerosis is frequently associated with important co-morbidities, mandating the search for better understanding and treat...

Aim: To evaluate the predictive roles of biochemical and complete blood count parameters in diagnosis febrile seizures by comparing these between patients with simple without seizures. Methods: One hundred fifty-two children (66 girls 86 boys), aged 6-60 months presenting fever symptoms to our hospital’s pediatric emergency department January 2015 2020 were included study. Demographic data, pa...

PURPOSE Febrile seizure, the most common type of pediatric convulsive disorder, is a benign seizure syndrome distinct from epilepsy. However, as epilepsy is also common during childhood, we aimed to identify the prognostic factors that can predict epilepsy in children with febrile seizures. METHODS The study comprised 249 children at the Korea University Ansan Hospital who presented with febr...

BACKGROUND Febrile seizure a common convulsion disorder in children, can lead to increased morbidity and mortality because of risk of aspiration and hypoxia during prolonged febrile seizures. There are many risk factors associated with febrile seizures and their recurrence. We conducted this study to see if there is a role of iron status in febrile seizures. METHODS This cross-sectional study...

background: serum prolactin level has been used as an alternative determinant to help differentiate epileptic from non-epileptic seizures. we aimed to analyze the association between serum prolactin concentration and epileptic seizure versus febrile seizure as well as seizure duration, single versus multiple seizure attacks and time lapse between seizure onset and blood sampling.   methods: sev...

OBJECTIVE Febrile seizure is the most common type of seizure in children. Their incidence is 2-5%. There are different hypotheses about relationship between neurotransmitters and trace elements (such as zinc) and febrile seizure. Zinc, as a major element of some enzymes, plays an important role in the central nervous system (CNS) and can affect some inhibitory mechanisms of CNS. The aim of the ...

This review focuses on the latest knowledge and understanding of febrile seizures and outlines the more important issues in the management of children who present with an apparent "febrile seizure". It is not the remit of this paper to discuss the detailed management of febrile seizures. Throughout this review, the words "partial" and "focal" will be used interchangeably and the term "febrile s...