Extracellular, large scale in vivo recording of neural activity is mandatory for elucidating the interaction of neurons within large neural networks at the level of their single unit activity. Technological achievements in MEMS-based multichannel electrode arrays offer electrophysiological recording capabilities that go far beyond those of classical wire electrodes. Despite their impressive cha...

It is standard practice to use benchmark datasets for comparing meaningfully the performance of a number of competing speaker identification systems. Generally, such datasets consist of speech recordings from different speakers made at a single point of time, typically in the same language. That is, the training and test sets both consist of speech recorded at the same point of time in the same...

We used single-channel kinetic analysis to study the inhibitory effects of tacrine on human adult nicotinic receptors (nAChRs) transiently expressed in HEK 293 cells. Single channel recording from cell-attached patches revealed concentration- and voltage-dependent decreases in mean channel open probability produced by tacrine (IC(50) 4.6 microM at -70 mV, 1.6 microM at -150 mV). Two main effect...

Apparent central apnoea (absent breathing movements) detected by monitoring movement of the thoracic wall was compared with simultaneous detection by abdominal wall movement. Eighteen infants provided one or more 24 hour recording of heart rate (electrocardiography), thoracic respiration (transthoracic impedance), and abdominal wall movement (pressure sensitive capsule distortion). Detection of...

Periodic visual stimulation and analysis of the resulting steady-state visual evoked potentials were first introduced over 80 years ago as a means to study visual sensation and perception. From the first single-channel recording of responses to modulated light to the present use of sophisticated digital displays composed of complex visual stimuli and high-density recording arrays, steady-state ...

We report a fully-integrated low-power 3-bit programmable-gain amplifier (PGA) that can be used as the second stage amplifier to adjust the gain for multi-channel neural recording systems. The design strategy maximizes energy-efficiency using a technique by optimizing a slew rate, gain and phase margin. The PGA consumes 8.66 μW from 1-V single supply. This is an order of magnitude lower than th...

We present a method for recording on-axis color digital holograms in a single shot. Our system performs parallel phase-shifting interferometry by using the fractional Talbot effect for every chromatic channel simultaneously. A two-dimensional binary amplitude grating is used to generate Talbot periodic phase distributions in the reference beam. The interference patterns corresponding to the thr...

We look at multiple-track detection for magnetic recording systems that use array heads to write and read over multiple tracks simultaneously. The recording channel is modeled as having intersymbol interference (ISI) in the axial direction, and intertrack interference (ITI) in the radial direction. Optimum multihead and single-head detectors are derived and analyzed in terms of error-probabilit...

The high-intensity, repetitive noise associated with functional magnetic resonance imaging hinders on-line monitoring of subjects' speech and/or recording speech signals suitable for off-line analysis. The proposed algorithm enhances the speech signal by suppressing the scanner noise in the signal recorded by a single-channel microphone. Significant increases in signal-to-noise ratio are achiev...