Micro/nanofluidic molecular sieving structures[1] have great potential for faster molecular separation. However, their use has been largely limited to big molecules such as DNA, since it is rather challenging to fabricate structures with near-molecular dimensions. We present a novel separation method using nanofluidic filters, which is based on the steric hindrance effect of molecules[2-4]. Whe...

This paper proposes a generalized multipath separability condition for subspace processing and derives a novel COD (Combined Oversampling and Displacement) algorithm to utilize both spatial and temporal diversities for path separation and DOA estimation. A unique advantage lies in its ability to cope with the situation where the number of multipaths is much larger than that of antenna elements,...

Pinched flow fractionation is shown to be an efficient and selective way to quickly separate particles by size in a very polydisperse semi-concentrated suspension. In an effort to optimize the method, we discuss the quantitative influence of the pinching intensity in the balance between the requirements of selectivity and minimal dilution.

Two variable step size (VSS) techniques are proposed for adaptive decorrelation filtering (ADF) to improve the performance of competing speech separation. The first VSS method applies gradient adaptive step-size (GAS) to increase ADF convergence rate. Under some simplifying assumptions, the GAS technique is generalized to allow the combination with additional VSS techniques for ADF algorithm. T...

Size and geometric control of nanomaterials are important to the discovery of intrinsic size/shape dependent properties and bottom up approaches for the fabrication of functional nanodevices. Two general strategies have been employed to create size-uniform nanocrystals. One method is direct particle size control during synthesis by adjusting growth parameters; 7–9] the other is post-synthesis s...

A novel microchip separation method for microparticles based on electromagnetophoresis was developed. In this method, a double Y-shape microchip with two inlets and two outlets was used for particle separation. Microparticles of two different sizes were suspended in an aqueous solution and introduced into the microchannel from one inlet with a stream of the aqueous solution without particles fr...

The formation of dynamical clusters of proteins is ubiquitous in cellular membranes and is in part regulated by the recycling of membrane components. Mean-field models of out-of-equilibrium cluster formation with recycling predict a broad cluster size distribution for infinite systems and must be corrected for finite-size effects for small systems such as cellular organelles. We show, using sto...

In microfluidic filtration systems, one of the leading obstacles to efficient, continuous operation is clogging of the filters. Here, we introduce a lateral flow microfluidic sieving (μ-sieving) technique to overcome clogging and to allow continuous operation of filter based microfluidic separation. A low frequency mechanical oscillation was added to the fluid flow, which made possible the rele...

In low-temperature processes, heat rejected from separation columns is removed by refrigeration systems to heat sinks (reboilers & pre-heaters), process streams, other <span style="font-size: 10pt; col...

Realizing the full potential of magnetic nanoparticles (MNPs) in nanomedicine requires the optimization of their physical and chemical properties. Elucidation of the effects of these properties on clinical diagnostic or therapeutic properties, however, requires the synthesis or purification of homogenous samples, which has proved to be difficult. While initial simulations indicated that size-se...