INTRODUCTION Diagnosis of atypical tuberculosis is difficult. Therefore, it is important that physicians are aware of rare presentations of tuberculosis to avoid diagnostic delays. CASE PRESENTATION We present the case of a 17-year-old Sri Lankan man who presented to our facility with an ill-defined large induration over the skin of his left buttock and thigh. A cause could not be found despi...

The use of ancient DNA in paleopathological studies of tuberculosis has largely been restricted to confirmation of disease identifications made by skeletal analysis; few attempts at obtaining genotype data from archaeological samples have been made because of the need to perform different PCRs for each genetic locus being studied in an ancient DNA extract. We used a next generation sequencing a...

Several treatment regimens with antituberculosis medicinal products are available for tuberculosis. Thiozonide is a newly developed original antimicrobial agent that exhibits bacteriostatic activity against Mycobacterium tuberculosis strains H37Rv, CN-37, CN-40, and MS-115. The aim of the study was to investigate embryotoxic, foetotoxic, teratogenic effects thiozonide in pregnant rabbits. Mater...

Aim of this study was to evaluate by Micro-CT the structure of cancellous bone samples collected from historical human vertebrae of subjects affected by tuberculosis. Tuberculosis (TB) is a potentially fatal contagious disease most often caused by Mycobacterium tuberculosis but also by M. bovis and, although seldom, by other Mycobacterium species (M. aviumintracellulare, M. africanum). It mainl...

Extrapulmonary tuberculosis accounts for approximately 10% of tuberculous infections; the musculoskeletal system is involved in a small number of these (10%). Skeletal tuberculosis is an indolent disease, and diagnosis may be delayed. Conventional methods are time consuming and have a low sensitivity rate. In recent years PCR-based protocols raised hopes as a reliable and fast diagnostic tool f...

Tuberculosis is the very communal infection found globally and can nearly all parts of human body be affected by it, mostly affect chest. Among tuberculosis skeletal system; 50% cases spinal cord. cord results in Gibbus deformity, edema, involvement intervertebral discs, epidural abscess, paravertebral abscess edema with bone destruction vertebrae collapse soft tissue planes. The most valuable ...

BACKGROUND Spinal tuberculosis is the most common form of skeletal tuberculosis. However, there were limited data to evaluate the trend of spinal tuberculosis research. This study aims to investigate the trend of spinal tuberculosis research and compare the contribution of research from different countries and authors. METHODS Spinal tuberculosis-related publications from 1994 to 2015 were re...

Osteitis fibrosa cystica (OFC) is a late sequela of untreated hyperparathyroidism caused by the autonomous secretion parathyroid hormone (PTH). It characterized bone pain, skeletal deformities, and pathological fractures. OFC hypersecretion PTH, leading to demineralization We report case unusual presentation in middle aged woman who noticed gradual shortening her height within particular period...