BACKGROUND Skin graft survival and healing requires rapid restoration of blood flow to the avascular graft. Failure or delay in the process of graft vascularization is a significant source of morbidity and mortality. One of the primary regulators of blood flow and vessel growth is nitric oxide (NO). The secreted protein thrombospondin-1 (TSP1) limits NO-stimulated blood flow and growth and comp...

PURPOSE To evaluate the outcomes of eyelid reconstruction in patients who underwent full thickness skin grafts. METHODS A retrospective, noncomparative intervention study of patients who underwent periocular reconstruction with full thickness skin grafts between 2005 and 2011. RESULTS One hundred consecutive Caucasian patients were included in the study, 54 women and 46 men. Mean follow up ...

Objectives: To evaluate the amnion graft in vaginoplasty, to assess the advantage of a flap placed over fourchette and to evaluate the benefit of gauze mould. Methods: Out of the 35 subjects of primary amenorrhea, eight with complete vaginal agenesis were selected for vaginoplasty. Half of these received split thickness skin graft and other half received amnion graft. An additional triangular f...

Crandall CG, Davis SL. Cutaneous vascular and sudomotor responses in human skin grafts. J Appl Physiol 109: 1524–1530, 2010. First published June 17, 2010; doi:10.1152/japplphysiol.00466.2010.—Each year millions of individuals sustain burns. Within the US 40,000–70,000 individuals are hospitalized for burn-related injuries, some of which are quite severe, requiring skin grafting. The grafting p...

INTRODUCTION Obesity and certain medical disorders make the reconstruction of skin defects challenging. Different kind of procedure can be used for these defect, besides, skin grafting is one of the most common and simplest procedure. Fat grafting and stem cells which are located in the adipose tissue have been commonly used in plastic surgery for regeneration and rejuvenation purposes. To decr...

PURPOSE Severe neck contracture is a problem that must be resolved by priority. We consider the best contracture treatment to be the full-thickness skin graft. However, clinicians often encounter patients, especially extensive burn patients, who have insufficient donor sites for the full-thickness skin graft. We treated extensive burn patients with neck scar contractures with a split-thickness ...

Objective To compare the outcomes of securing full-thickness skin grafting (FTSG) with through-and-through mattress suturing versus the classic tie-over and pressure dressing and identify the associated risk factors of graft failure. Methods A single-institution, retrospective case series of patients who had undergone excision of head and neck skin lesions requiring FTSG over a 10-year period...

A skin autograft is described as the transfer of without aid a blood supply from donor location to recipient site. The epidermis and portions underlying dermis are transferred using split-thickness grafts (STSGs). whole layer harvested for full-thickness (FTSGs) used transplant. installation methods usage STSGs discussed above. Graft movement, which impedes neovascularization promotes fluid acc...