نتایج جستجو برای: skp

تعداد نتایج: 304  

Journal: :Jurnal MSDA 2023

This study examined the implementation of electronic performance (e-performance) appraisal for Civil Servants, and identified obstacles efforts made. A qualitative descriptive method with an inductive approach was used, while data were collected through observation, documentation, interviews. The then analyzed several steps; reduction, display, inference. Findings indicate that assessments Serv...

Journal: :Masalah-masalah hukum 2023

Hubungan antara wajib pajak dengan fiskus kadangkala diwarnai adanya sengketa pajak. Keluarnya undang-undang Pengadilan Pajak menimbulkan anggapan bahwa semua pajak, satu-satunya pengadilan yang mempunyai kompetensi menyelesaian adalah Pajak. Faktanya banyak di bidang perpajakan diajukan ke lain selain salah satunya PTUN. Tulisan ini mengkaji batasan kewenangan mengadili Batasan dan PTUN atas S...

Journal: :Bhm Berg- Und Hüttenmännische Monatshefte 2023

Abstract The aim of this contribution is to present a comprehensive approach study the extent hydrogen entry into hot-dip-galvanized DP1000 steel, which exposed corrosive conditions. For purpose, Z100 coating was immersed in 5% sodium chloride solution at room temperature. distribution and spots increased were detected with scanning Kelvin probe (SKP) force microscopy (SKPFM). Effects inserted ...

Journal: :International journal of pure and applied sciences 2021

One of the important arguments that will carry today's world to high technology future is rare earth elements. However, energy be most field in and also, issue fusion energy. Of course, as all areas technology, elements make an contribution development technology. Also, nuclear structure physics has always been focus interest still a subject frequently studied today. Therefore, this study, grou...

2008
Stephanie G Willis Jutta Deininger Keiichi I Nakayama Brian J Druker Anupriya Agarwal Thomas GP Bumm Amie S Corbin Thomas O'Hare Marc Loriaux Thomas G.P. Bumm Amie S. Corbin Thomas O’Hare Jonathan VanDyke Stephanie G. Willis Keiichi I. Nakayama Brian J. Druker Michael W. Deininger

BCR-ABL is proposed to impair cell cycle control by disabling p27, a tumor suppressor that inhibits cyclin-dependent kinases. We show that in cell lines p27 expression is inversely correlated with expression of SKP2, the F-box protein of SCF, the E3 ubiquitin ligase that promotes proteasomal degradation of p27. Inhibition of BCR-ABL kinase causes G1 arrest, downregulation of SKP2 and accumulati...

Journal: :Työväentutkimus 2022

Käsittelen tässä artikkelissa Suomen Kansan Demokraattisen Liiton (SKDL) ja Kommunistisen Puolueen (SKP) kulttuuripolitiikkaa sodanjälkeisistä vuosista kommunismin romahtamiseen saakka. Valotan SKDL:n SKP:n kulttuuripolitiikan suuria päämääriä eri aikakausina tarkastelemalla niiden kulttuuripoliittisia linjoja yleisellä tasolla. Artikkeli perustuu tuottamiin julkaisuihin, liitto- edustajakokous...

Journal: :Journal of virology 2011
Andrey A Tokarev Jason Munguia John C Guatelli

The HIV-1 protein Vpu counteracts the antiviral activity of the innate restriction factor BST-2/tetherin by a mechanism that partly depends on its interaction with β-TrCP, a substrate adaptor for an SCF (Skp-Cullin 1-F box) E3 ubiquitin ligase complex. This suggests that Vpu stimulates the ubiquitination of BST-2 and that this underlies the relief of restriction. Here, we show that Vpu stimulat...

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