HE literature on the genetic and antigenic basis of tumor transplantation has T been reviewed by BITTNER (1935), LITTLE (1941; 1947), HAUSCHKA, (1952) and SNELL (1953b, c). In mice, the genetic loci involved were named “histocompatibility” loci by SNELL (1948), the prefix “histo” being used to denote the probable similarity of genes determining reactions to neoplastic and normal tissue transpla...

Rosenblatt's transformation has been used extensively for evaluation of model goodness-of-fit, but it only applies to models whose joint distribution is continuous. In this paper we generalize the transformation so that it applies to arbitrary probability models. The transformation is simple, but has a wide range of possible applications, providing a tool for exploratory data analysis and forma...

At the finest scale of our coarse-to-fine alignment strategy, we require an alignment technique which performs well given large tile sizes but a very small search radius. In this context, techniques such as our previously-described fast subpixel L2 alignment, or even simpler techniques such as phase correlation [Kuglin and Hines 1975] are outperformed by a well-implemented brute-force procedure...

In this article, we discuss the effect of removing the independence assumptions between the residuals in two-level random effect models. We first consider removing the independence between the Level 2 residuals and instead assume that the vector of all residuals at the cluster level follows a general multivariate normal distribution. We demonstrate how this assumption can allow us to fit higher...

We study the behavior of the conjugate-gradient method for solving a set of linear equations, where the matrix is symmetric and positive definite with one set of eigenvalues that are large and the remaining are small. We characterize the behavior of the residuals associated with the large eigenvalues throughout the iterations, and also characterize the behavior of the residuals associated with ...

At the finest scale of our coarse-to-fine alignment strategy, we require an alignment technique which performs well given large tile sizes but a very small search radius. In this context, techniques such as our previously-described fast subpixel L2 alignment, or even simpler techniques such as phase correlation [Kuglin and Hines 1975] are outperformed by a well-implemented brute-force procedure...