The objective of the present study was to compare the efficacy of functional endoscopic dilatation sinus surgery (FEDS) with functional endoscopic sinus surgery (FESS) in treatment of chronic rhinosinusitis in patients who failed medical therapy. We enrolled 24 patients suffering with chronic rhinosinusitis, who failed medical treatment and were proceeding to surgery, in a prospective, randomiz...

OBJECTIVE To assess quality of life (QOL) in patients with sinonasal symptoms in response to hypertonic saline nasal irrigation (HSNI), and to assess HSNI use patterns. STUDY DESIGN AND SETTING The study was an uncontrolled 12-month follow-up to a randomized controlled trial (RCT) and used HSNI in a community setting. We included 54 participants with recurrent or chronic sinonasal symptoms. F...

Background This study aims to evaluate the effect of COVID-19 lockdown period on chronic rhinosinusitis (CRS) symptoms control. Methodology cross-sectional was carried out adult patients (aged ≥18 years) who visited King Abdulaziz University Hospital within six months before starting date. information, including patients' diagnosis, presence rhinitis, number previous surgeries, and medications,...

BACKGROUND Previous studies describe the financial burden of chronic rhinosinusitis (CRS) from the perspective of third-party payers, but, to our knowledge, none analyze the costs borne by patients (i.e., out-of-pocket expenses [OOPE]). Furthermore, this burden has not been previously investigated in the context of a publicly funded health care system. OBJECTIVE The purpose of this study was ...

BACKGROUND A multicenter study (BREATHE I - Entellus Medical, Inc.) was performed to assess the safety and outcomes of a new, less invasive system that uses direct endoscopic visualization to facilitate balloon dilation of the maxillary sinus ostia and ethmoid infundibulum. General anesthesia was avoided in most subjects to assess feasibility of performing transantral ostial dilatation in an of...

OBJECTIVES/HYPOTHESIS To evaluate the efficacy of canine fossa puncture (CFP) by comparing patients with unilateral chronic rhinosinusitis (CRS) accompanying nasal polyposis (NP) who underwent CFP with those who underwent maxillary sinus clearance through a middle meatal antrostomy (MMA). STUDY DESIGN Prospective randomized study. METHODS Twenty-nine patients were randomly assigned to the C...

OBJECTIVES/HYPOTHESIS To determine the tolerability of xylitol mixed with water as a nasal irrigant and to evaluate whether xylitol nasal irrigation results in symptomatic improvement of subjects with chronic rhinosinusitis. STUDY DESIGN A prospective, randomized, double-blinded, controlled crossover pilot study. METHODS Twenty subjects were instructed to perform sequential 10-day courses o...

BACKGROUND The objectives of this study were, first, to confirm the presence of multiple domains within the Sino-Nasal Outcome Test 20 (SNOT-20) using a medically treated population, and, second, to reanalyze data from this population to reveal incremental information. A prospective, randomized controlled trial was performed. METHODS One hundred twenty-seven adults with chronic rhinitis or rh...