our previous studies on thalassemia patients, homozygous or compound heterozygous for severe beta thalassemia mutations, has suggested that 5’hs4-lcr and/or xmn1-hbg2 backgrounds, which were linked in our thalassemia patients, are important in determining the blood transfusion dependency of these individuals. while the majority of patients with aa/-- 5’hs4/xmn1 background, were severely depende...

background:confirmation of olive oil authenticity and particularly virgin olive oil has a great importance. several advanced chemical and genetic analyses have been used to monitor especial components; however each has its limitations especially when detecting hazelnut-adulterated olive oil. objectives:the objective of this research is to assess the presence of trace amount of hazelnut oil in o...

the melanocortin-1 receptor mc1r is encoded by the extension locus, playing a fundamental role in the determination of coat color in a number of mammalian species. however, so far there has been no report regarding the single nucleotide polymorphisms (snps) of the mc1r promoter region and the potential association of its snps with coat color in sheep (ovis aries). throughout the present study, ...

background: multiple sclerosis (ms), a chronic inflammatory demyelinating disorder with neurodegenerative aspects, is more common among young adults, particularly women. methods: this molecular study was designed to investigate the il-7r α chain gene in iranian ms patients. we studied 60 ms patients, diagnosed based on 2005 r-mcdonald criteria and 60 apparently healthy individuals as the contro...

There have been few studies on predictive biomarkers that may be useful to select the most suitable opioids optimize therapeutic efficacy in individual patients with cancer pain. We recently investigated of morphine and oxycodone using single nucleotide polymorphisms (SNPs) catechol‑O‑methyltransferase (COMT) rs4680 gene as a biomarker (RELIEF study). To explore additional enable selec...

Sorghum (Sorghum bicolor L.) is a promising biomass crop with high yields of cellulose, hemicellulose, and lignin. has emerged as an eco-friendly industrial material useful for producing biofuels bioplastics. This study conducted genotyping-by-sequencing (GBS)-based genome-wide association studies (GWAS) to establish the genetic basis traits associated biomass. Specifically, researchers evaluat...

Globally terminal drought is one of the major constraints to chickpea ( Cicer arietinum L.) production. Early flowering genotypes escape drought, and increase in seed size compensates for yield losses arising from drought. A MutMap population early large was developed by crossing mutant line ICC4958-M3-2828 with wild-type ICC 4958. Based on phenotyping population, extreme bulks days 100-seed we...

The enormous genetic diversity in South Asia resulting from a long and complex admixture history resulted the emergence of variation various traits variations disease susceptibility. Neuropsychological disorders are one such example that shows at population level. In this study, we aimed understanding neuropsychological level among Asian populations by curating, comparing contrasting single nuc...

Pojava rezistentnosti na insekticide kod kukaca ozbiljan je i rastući problem u poljoprivrednoj proizvodnji. Razvijanjem učinkovitih programa praćenja omogućava se rano otkrivanje te razvoj pravovremena implementacija antirezistentnih strategija. Polimorfizam pojedinačnog nukleotida, engl. Syngle Nucleotide Polymorphisms (SNPs), novija metoda analize cijelog genoma utvrđivanjem polimorfizma poj...

background and purpose: microorganism-based synthesis of nanostructures has recently been noted as a green method for the sustainable development of nanotechnology. nowadays, there have been numerous studies on the emerging resistant pathogenic bacteria and fungal isolates, the probable inability of bacteria and fungi to develop resistance against silver nanoparticles’ (snps) antibacterial, ant...