Solar radiation is essential for the evolution of life on earth. radiation, including ultraviolet (UV), reaches earth's surface. The sun emits three types UV radiation: UVA, UVB, and UVC, which have beneficial harmful effects human body. most important benefit synthesis vitamin D in skin. However, UVB also causes direct photochemical damage to DNA. This study aimed investigate ability compound ...

The ultraviolet radiation present in sunlight is the primary cause of nonmelanoma skin cancer and has been implicated in the development of cutaneous malignant melanoma. In addition, ultraviolet is immune suppressive and the suppression induced by ultraviolet radiation has been identified as a risk factor for skin cancer induction. Ultraviolet also suppresses the immune response to infectious a...

Because solar UV-radiation represents the most important environmental risk factor for the development of non-melanoma skin cancer, UV protection is important to prevent these malignancies. Consequently, public health campaigns were developed to improve the knowledge of the general population regarding the role of UV-radiation for the development of skin cancer. However, it has to be noted that...

There is a growing interest for vitamin D in the medical and scientific community as well as in the public medias as illustrated by a huge number of publications. Most experts claim that vitamin D deficiency/insufficiency is widespread with potential important public health consequences. It may seem surprising for many persons that a deficiency in a vitamin may be so frequent in countries where...

Amphibians are currently suffering a period of mass extinction with approximately 20% of species under severe threat and more than 120 species already extinct. In light of this crisis there is an urgency to establish viable ex situ populations and also find the causes of in situ declines. The role of ultraviolet radiation and Vitamin D(3) in amphibian health directly influences both ex situ and...

Low vitamin D status is common in Europe. The major source of vitamin D in humans is ultraviolet B (UVB)-induced dermal synthesis of cholecalciferol, whereas food sources are believed to play a lesser role. Our objectives were to assess UVB availability (Jm(-2)) across several European locations ranging from 35° N to 69° N, and compare these UVB data with representative population serum 25-hydr...

The purpose of this review is to summarize the peer-reviewed literature in relation to sunlight exposure assessment and the validity of using sunlight exposure questionnaires to quantify vitamin D status. There is greater variability in personal ultraviolet (UV) light exposure as the result of personal behavior than as the result of ambient UV light exposure. Although statistically significant,...

PURPOSE OF REVIEW To highlight the human studies published over the past year examining the influence of vitamin D on risk of colorectal cancer. RECENT FINDINGS Studies over the past year have added more support to the idea that higher levels of vitamin D may decrease risk of colorectal cancer. Further, typical dietary intakes such as 200-400 IU/day may be too low to exert appreciable benefit...

Exposure to solar UV radiation is a double-edged sword: the benefits include vitamin D3 production and tanning, while the risks include diseases linked to free-radical production and DNA damage. Research during the past few years has demonstrated that the health benefits of solar UVB (290–315 nm), the primary source of vitamin D3 for many people, now include reduced risk for bone diseases, many...

Starting in the 1980s, largely observational evidence mounted that solar ultraviolet-B (UVB) irradiance and vitamin D reduce the risk of many types of cancer. Based on observational studies, it is estimated that 1500 and 3600 International Units (IU) of vitamin D3 are required daily for a 50% reduction in risk of colorectal and breast cancer, respectively. A recent randomized, double-blind, pla...