background and objectives: salmonella is an important food-borne pathogen in humans. strains of salmonella spp. that producing extended-spectrum β-lactamases have become a concern in medicine regarding both antimicrobial treatment and infection control program. the objective of this study was to describe the antibiotic susceptibility, esbl production and determining the prevalence of the bla ct...

Left-right (LR) asymmetry (handedness, chirality) is a well-conserved biological property of critical importance to normal development. Changes in orientation of the LR axis due to genetic or environmental factors can lead to malformations and disease. While the LR asymmetry of organs and whole organisms has been extensively studied, little is known about the LR asymmetry at cellular and multic...

Global descriptors of the cognitive phenotype of Turner syndrome are well established and are thus commonly referred to. For example, Turner syndrome is a proposed etiology of the nonverbal learning disability - because of reported relative strengths in verbal skills, and relatively weaker nonverbal skills - particularly in arithmetic, select visuospatial skills, and processing speed. This prof...

OBJECTIVES To explore the correlation of serum IgG4 (sIgG4) with clinical manifestations or therapeutic response in rheumatoid arthritis (RA). METHODS Consecutive 136 RA patients were recruited and followed up at regular interval. SIgG4 was detected by immunonephelometry. Serial synovial tissue sections from 46 RA patients were stained immunohistochemically for IgG4. RESULTS Forty-six perce...

microdeletion syndromes are contiguous gene deletion syndromes of less than 5 megabases.  most often, many of these syndromes are not detectable by  routine chromosomal analysis and require more specific testing techniques such as fish or more accurate general coverage like array comparative genomic hybridization.  as many of these syndromes are phenotypically recognizable and allow for easy cl...

A popular method for reconstructing gene networks from micro-array data is Bayesian structure learning. However, most Bayesian structure learning algorithms suffer from three major shortcomings, i.e., the high computational cost, inefficiency in exploring qualitative knowledge, and inability of reconstructing phenotype specific gene network. We address these three short-comings by presenting a ...

Aim : The aims of the present study were to explore relations between gingival phenotype (GP) and periodontal health status find prevalence a specific in small Bulgarian population. Materials methods We recruited 50 patients attending our dental practice with different diagnoses. A detailed was taken assess diagnosis each participant. Several clinical for evaluation thickness keratinized tissue...

Summary Phenotype prediction is a key goal for medical genetics. Unfortunately, most genome-wide association studies are done in European populations, which reduces the accuracy of predictions via polygenic scores non-European populations. Here, we use population genetic models to show that human demographic history and negative selection on complex traits can result population-specifi...