نتایج جستجو برای: spent fuel transportation cask
تعداد نتایج: 157653 فیلتر نتایج به سال:
Pyrochemical processes are under development at Argonne National Laboratory for recovery of transuranium (TRU) elements from light water reactor spent fuel. The recovered TRU elements will be used as fuel in the integral fast reactor (IFR). Burning these long-lived isotopes for electrical power generation has the additional benefit of reducing the burden on the geological repository for their l...
This study compares the proliferation resistance of DUPIC (Direct Use of Spent PWR Fuel in CANDU) fuel cycle with other fuel cycle cases. The other fuel cycles considered in this study are PWR of once-through mode (PWR-OT), PWR of reprocessing mode (PWR-MOX), in which spent PWR fuel is reprocessed and recovered plutonium is used for making MOX (Mixed Oxide), CANDU with once-through mode (CANDU-...
Mammalian Lin-2 (mLin-2)/CASK is a membrane-associated guanylate kinase (MAGUK) and contains multidomain modules that mediate protein-protein interactions important for the establishment and maintenance of neuronal and epithelial cell polarization. The importance of mLin-2/CASK in mammalian development is demonstrated by the fact that mutations in mLin-2/CASK or SAP97, another MAGUK protein, le...
BACKGROUND Heterozygous loss-of-function mutations in the X-linked CASK gene cause progressive microcephaly with pontine and cerebellar hypoplasia (MICPCH) and severe intellectual disability (ID) in females. Different CASK mutations have also been reported in males. The associated phenotypes range from nonsyndromic ID to Ohtahara syndrome with cerebellar hypoplasia. However, the phenotypic spec...
It is generally recognized that the spent fuel discharged from nuclear power plants constitutes the main contribution to nuclear waste. The management of spent fuel from nuclear power plants differs depending on the perspectives and scenarios posed by the countries directly concerned. However, there is a general consensus on the need for a deep geological repository and a reduction in the burde...
The factors influencing the level of U-232 contamination in U-233 are examined for heavy-water-moderated, light-water-moderated and liquid-metal cooled fast breeder reactors fueled with natural or low-enriched uranium and containing thorium mixed with the uranium or in separate target channels. U-232 decays with a 69-year half-life through 1.9-year half-life Th-228 to Tl-208, which emits a 2.6 ...
All known protein kinases, except CASK [calcium/calmodulin (CaM)-activated serine-threonine kinase], require magnesium ions (Mg(2+)) to stimulate the transfer of a phosphate from adenosine 5'-triphosphate (ATP) to a protein substrate. The CaMK (calcium/calmodulin-dependent kinase) domain of CASK shows activity in the absence of Mg(2+); indeed, it is inhibited by divalent ions including Mg(2+). ...
Calcium (Ca(2+)) and Calmodulin (CaM)-dependent serine/threonine kinase II (CaMKII) plays a central role in synaptic plasticity and memory due to its ability to phosphorylate itself and regulate its own kinase activity. Autophosphorylation at threonine 287 (T287) switches CaMKII to a Ca(2+) independent and constitutively active state replicated by overexpression of a phosphomimetic CaMKII-T287D...
RATIONALE Mechanisms underlying membrane protein localization are crucial in the proper function of cardiac myocytes. The main cardiac sodium channel, NaV1.5, carries the sodium current (INa) that provides a rapid depolarizing current during the upstroke of the action potential. Although enriched in the intercalated disc, NaV1.5 is present in different membrane domains in myocytes and interacts...
CASK is a unique MAGUK protein that contains an N-terminal CaM-kinase domain besides the typical MAGUK domains. The CASK CaM-kinase domain is presumed to be a catalytically inactive pseudokinase because it lacks the canonical DFG motif required for Mg2+ binding that is thought to be indispensable for kinase activity. Here we show, however, that CASK functions as an active protein kinase even wi...
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