This paper describes an unusual association of aspermia and untreatable, chronic testicular pain in a young man who underwent 14 surgical interventions for an imperforate anus. Physical examination and ultrasonography revealed left epididymal and vas enlargement, normal-sized testes, tubular ectasia of the left rete testis and a small intraprostatic paramedian left cyst. Retrograde ejaculation ...

Males that follow alternative reproductive tactics might differ in their investment into testis development and sperm production. The resource-allocation hypothesis predicts that males following a sneaker tactic should invest more into sperm production than dominant territorial males which should invest more into mate guarding. This hypothesis is supported by studies in species where individual...

We have found that the rat testis contains a cell surface galactosyl receptor that is antigenically related to the minor species of rat liver asialoglycoprotein receptor (ASGP-r) and has binding affinity for galactose coupled to agarose. In immunoblotting experiments, rat testis galactosyl receptor (RTG-r) is recognized by antiserum raised against the minor ASGP-r species of rat liver (designat...

Extra-embryonic tissue-spermatogenesis-homeobox gene 1 (Esx1) encodes an X-linked homeobox protein. Despite the fact that the temporal and spatial mRNA expression pattern of the protein has been studied extensively in the testis, specific localisation of ESX1 in the testis remains to be determined. In the present study, we generated ESX1 antiserum to investigate the stage- and tissue-specific e...

While early models of ejaculate allocation predicted that both relative testes and ejaculate size should increase with sperm competition intensity across species, recent models predict that ejaculate size may actually decrease as testes size and sperm competition intensity increase, owing to the confounding effect of potential male mating rate. A recent study demonstrated that ejaculate volume ...

Although a subset of the olfactory receptor (OR) gene family is expressed in testis, neither their developmental profile nor their physiological functions have been fully characterized. Here, we show that MOR23 (a mouse OR expressed in the olfactory epithelium and testis) functions as a chemosensing receptor in mouse germ cells. In situ hybridization showed that MOR23 was expressed in round spe...

Olfactory receptors constitute a huge family of structurally related G protein-coupled receptors, with up to a thousand members expected. We have shown previously that genes belonging to this family were expressed in the male germ line from both dog and human. The functional significance of this unexpected site of expression was further investigated in the present study. We demonstrate that a f...

two glycoprotein sperm-specific antigens of testicular origin and twelve seminal plasma antigens which coated the spermatozoa during passage through the reproductive tract. Two of the sperm-coating antigens originated in the testis, two in the epididymis and eight above the level of the vas deferens. Relationships between sperm-coating antigens and capacitation, and sperm-coating antigens and p...

background: the study of specific genes expressed in the testis is important to understanding testis development and function. spermatogenesis is an attractive model for the study of gene expression during germ cell differentiation. spermatogenesis associated-19 (spata-19) is a recently-identified important spermatogenesis-related gene specifically expressed in testis. its protein product is in...

background: artesunate is commonly used in malaria therapy. many antimalarial drugs have been associated with male reproductive dysfunction. the effect of artesunate on male reproductive activities was studied using in–vivo and in-vitro experimental models. methods: adult male rats (n=6) were orally given artesunate (2.9 mg/kg body weight) on daily basis for five days. artesunate (2.9 mg/kg bod...