Using capillary electrophoresis combined with tandem mass spectrometry, we have developed a method to simultaneously detect lorazepam, clonazepam, temazepam, oxazepam, diazepam, and nitrazepam in urine. The urine samples were submitted to a modified QuEChERS extraction procedure, followed by electrophoretic separation in 0.1 M formic acid electrolyte (pH 2.4) using a polyvinyl alcohol (PVA)-coa...

A multiresidue analysis of pesticides in tea using supercritical fluid extraction (SFE) and GC-MS was developed. The preprocessing using SFE shortened the total analysis time. The SFE extract contained less matrices than the extract obtained with organic solvents. However, these matrices disturbed instrumental analysis. So, the extract was cleaned up with ENVI™-Carb/NH2 and InertSep™ SI cartrid...

Validation of methods for microbial detection in foods or other matrices involves determining microbe recoveries. Recoveries are expressed qualitatively as presence-absence data, which are obtained from quantitative spiking experiments. Replicate samples of foods are spiked with the microbe of interest, generally at several concentration levels. Usually three different levels are used. However,...

A method of on-line pretreatment coupled to HPLC with fluorescence detection was developed and validated for the determination of nine quinolones in honey samples. This method simplified the complicated process of sample pretreatment and reduced sample treatment time. Recovery of the quinolones was between 92% 101% for spiked honey samples. The limit of detection was 0.22 3.78 ng/mL (signal/noi...

A simple and accurate method for the quantitative retention of traces of selenium (IV) from aqueous media was developed employing polyurethane foams (PUFs).The dependences of selenium (IV) uptake by the unloaded and tributyl phosphate (TBP) plasticized PUFs on pH, salt effect, nature and concentration of surfactant, etc. was critically studied. The sorption data have followed Langmuir, and Dubi...

Suppressed ion chromatography with a conductivity detector was developed for the determination of trace amounts of underivatized chloroacetic acids (CAAs). When sodium carbonate and methanol were used as a mobile phase, the simultaneous determination of each CAA took approximately 25 min. The linearity, reproducibility and detection limits were determined for the proposed method. For the solid-...

This paper describes the application of IP Method 585 for measuring trace amounts of FAME in jet fuel using the Agilent 5975C GC/MS system. This method uses selective ion monitoring (SIM) to improve FAME selectivity and sensitivity in the complex jet fuel sample matrix. This was demonstrated by running jet fuel samples spiked with known quantities of soybean biodiesel FAMEs. Full recovery of th...

This article details the elements used in the method verification for the simultaneous high performance liquid chromatography (HPLC) assay of Pentoxifylline, Mupirocin, Itraconazole, and Fluticasone Propionate in HumcoTM Lavare Wound base. The method was proven to be linear over 50%–150% of the nominal concentration of the standards. The method was proven to be accurate over 50%–150%, with 98%–...

BACKGROUND To experimentally determine the survival kinetics of influenza virus on personal protective equipment (PPE) and to evaluate the risk of virus transfer from PPE, it is important to compare the effects on virus recovery of the method used to contaminate the PPE with virus and the type of eluent used to recover it. METHODS Avian influenza virus (AIV) was applied as a liquid suspension...

To confirm the method for preparing artificially spiked soil with polycyclic aromatic hydrocarbons (PAHs), we tested the homogeneity of PAHs in spiked soils, which were prepared by three different procedures, by using kaolin and ando soil. When the slurry of kaolin and acetone containing PAHs were evaporated by a rotary evaporator at 30 - 35 degrees C, the most homogeneous distribution of PAHs ...